Zhu Chunsu, Lian Zhiwei, Sun Jing, Huang Yongying, Li Shengmei, Zhang Heng, Wang Jianmin
Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420, Fuma Road, Jinan District, Fuzhou, 350014, China.
Fujian Key Laboratory of Advanced Technology for Cancer Screening and Early Diagnosis, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
BMC Geriatr. 2025 Aug 30;25(1):675. doi: 10.1186/s12877-025-06345-2.
Although studies have demonstrated that both lifestyles and subjective well-being (SWB) are associated with mortality risk, the joint effects of a healthy lifestyle and SWB on the risk of mortality are unclear. This study aimed to explore the combined impact of lifestyles and SWB on total mortality among the older Chinese population.
Data were obtained from the Chinese Longitudinal Healthy Longevity Survey conducted from 2002 to 2018. A total of 13,282 participants aged ≥ 65 years were included. SWB was measured by an eight-item tool covering life satisfaction, optimism, conscientiousness, anxiety, loneliness, personal control, feeling useless, and happiness. A total healthy lifestyle score was calculated by summing across five lifestyle factors (smoking, drinking, exercise, dietary diversity and body mass index), ranging from 0 to 5, and was categorized into the following groups: healthy (4-5 points), intermediate (2-3 points) and unhealthy (0-1 point). Cox proportional regression analyses were carried out adjusting for demographic characteristics and other potential confounders.
In total, 8549 (64.4%) deaths were reported during the follow-up period. Compared with the higher healthy lifestyle score, the hazard ratios (HRs) for all-cause mortality for the intermediate and unhealthy lifestyle scores were 1.11 (1.04-1.17) and 1.17 (1.09-1.26), respectively, independent of SWB. A similar relationship between SWB and total mortality was observed, independent of lifestyle factors. The participants who had worse SWB experienced a 1.19 (1.14-1.25) higher risk of total mortality in comparison with those who had better SWB after adjusting for lifestyles. Combinations of unhealthy lifestyle scores and poor SWB were associated with an increased risk of total mortality, and the highest risk was found among participants with a healthy lifestyle score of 0-1 and worse SWB (HR = 1.41, 95% CI = 1.28-1.55).
A stronger risk of total mortality was found when worse SWB and unhealthy lifestyle occurred together, suggesting that a comprehensive approach to healthy lifestyle and SWB might be a potential strategy to improve longevity.
尽管研究表明生活方式和主观幸福感(SWB)均与死亡风险相关,但健康生活方式和主观幸福感对死亡风险的联合影响尚不清楚。本研究旨在探讨生活方式和主观幸福感对中国老年人群全因死亡率的综合影响。
数据来自于2002年至2018年进行的中国健康与养老追踪调查。共纳入13282名年龄≥65岁的参与者。主观幸福感通过一个包含生活满意度、乐观主义、尽责性、焦虑、孤独感、个人掌控感、无用感和幸福感的八项工具进行测量。通过对五个生活方式因素(吸烟、饮酒、运动、饮食多样性和体重指数)进行求和计算出总的健康生活方式得分,范围为0至5,并分为以下几组:健康(4 - 5分)、中等(2 - 3分)和不健康(0 - 1分)。进行Cox比例回归分析,并对人口统计学特征和其他潜在混杂因素进行了调整。
在随访期间,共报告了8549例(64.4%)死亡病例。与较高的健康生活方式得分相比,中等和不健康生活方式得分的全因死亡率风险比(HR)分别为1.11(1.04 - 1.17)和1.17(1.09 - 1.26),与主观幸福感无关。在不考虑生活方式因素的情况下,也观察到主观幸福感与全因死亡率之间存在类似的关系。在对生活方式进行调整后,主观幸福感较差的参与者与主观幸福感较好的参与者相比,全因死亡率风险高出1.19(1.14 - 1.25)倍。不健康生活方式得分与较差的主观幸福感相结合与全因死亡率风险增加相关,在健康生活方式得分为0 - 1分且主观幸福感较差的参与者中发现风险最高(HR = 1.41,95%CI = 1.28 - 1.55)。
当较差的主观幸福感和不健康生活方式同时出现时,发现全因死亡率风险更高,这表明综合关注健康生活方式和主观幸福感可能是提高长寿的潜在策略。