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M1-BMDMs with Wnt5a deletion attenuate liver fibrosis by suppression of Wnt5a/Frizzled 2 axis in hepatic progenitors.

作者信息

Xing Fei-Fei, Wang Dan-Yang, Xu Yan-Nan, Zheng Xin-Rui, Zhang Shi-Hao, Zong Meng-Yao, Zhan Jun-Yi, Wang De-Xin, Liu Wei, Chen Jia-Mei, Chen Gao-Feng, Liu Ping, Liu Cheng-Hai, Mu Yong-Ping

机构信息

Institute of Liver Diseases, Key Laboratory of Liver and Kidney Disease of the Ministry of Education, Clinical Key Laboratory of TCM of Shanghai, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine (TCM), Shanghai University of TCM, 528, Zhangheng Road, Pudong District, Shanghai, 201203, China.

出版信息

Cell Biosci. 2025 Aug 30;15(1):125. doi: 10.1186/s13578-025-01467-x.

DOI:10.1186/s13578-025-01467-x
PMID:40885967
Abstract
摘要

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[10]
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本文引用的文献

[1]
Intravital imaging: dynamic insights into liver immunity in health and disease.

Gut. 2024-7-11

[2]
Hepatic progenitor cell-originated ductular reaction facilitates liver fibrosis through activation of hedgehog signaling.

Theranostics. 2024-3-25

[3]
Myeloid-derived Wnts play an indispensible role in macrophage and fibroblast activation and kidney fibrosis.

Int J Biol Sci. 2024-4-8

[4]
A new era of macrophage-based cell therapy.

Exp Mol Med. 2023-9

[5]
Role of macrophage polarisation in skin wound healing.

Int Wound J. 2023-9

[6]
Identification of a rare Gli1 progenitor cell population contributing to liver regeneration during chronic injury.

Cell Discov. 2022-11-1

[7]
Distinct spatial distribution and roles of Kupffer cells and monocyte-derived macrophages in mouse acute liver injury.

Front Immunol. 2022

[8]
Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis.

J Clin Invest. 2022-6-15

[9]
WNT5A promotes the metastasis of esophageal squamous cell carcinoma by activating the HDAC7/SNAIL signaling pathway.

Cell Death Dis. 2022-5-20

[10]
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators.

Annu Rev Biochem. 2022-6-21

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