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STONE及新STONE评分在老年输尿管结石患者中的验证:一项回顾性队列研究

Validation of the STONE and new STONE score for ureteral stones in elderly patients: a retrospective cohort study.

作者信息

Altundağ İbrahim, Koçer Mehmet Taylan

机构信息

Department of Emergency Medicine, University of Health Sciences, Haydarpaşa Numune Training and Research Hospital, Selimiye, Tıbbiye Cd No:23, Üsküdar, 34668, Istanbul, Turkey.

Department of Emergency Medicine, Tekirdağ Dr. İsmail Fehmi Cumalioğlu City Hospital, İstiklal, Yemen Sokak No: 13, Süleymanpaşa, 59030, Tekirdağ, Turkey.

出版信息

Urolithiasis. 2025 Aug 31;53(1):167. doi: 10.1007/s00240-025-01843-9.

DOI:10.1007/s00240-025-01843-9
PMID:40886201
Abstract

Ureteral stones are a common cause of emergency department visits. However, their presentation in older adults may be atypical. As the global population ages, effective and low-risk diagnostic strategies are increasingly vital to improve patient outcomes, reduce radiation exposure, and lower healthcare costs. This retrospective cohort study conducted between January 2020 and December 2024. We aimed to assess the diagnostic performance of the STONE and New STONE scores in detecting ureteral stones among patients aged 60 and older presenting with flank pain. A total of 161 patients who underwent abdominal computed tomography (CT) were included, with ureteral stones detected in 48.4%. Patients with stones had significantly higher STONE (8.7 ± 2.0 vs. 6.1 ± 1.9) and New STONE scores (5.0 ± 1.9 vs. 2.7 ± 1.6) compared to patients without stone (p < 0.001 for both). The STONE score showed an AUC of 0.830 and the New STONE score 0.829. A cut-off STONE score > 5 yielded 97.4% sensitivity, while a cut-off > 9 provided 88.0% specificity. For the New STONE score, a cut-off > 3 offered 89.7% sensitivity, and a cut-off > 6 showed 97.6% specificity. Both scores demonstrated reliable diagnostic accuracy in elderly patients. The STONE score favored sensitivity, while the New STONE score favored specificity. Our findings suggest that these scoring systems may support imaging decision-making and contribute to reducing unnecessary CT exposure and healthcare costs in older adults with suspected ureteral stones.

摘要

输尿管结石是急诊就诊的常见原因。然而,它们在老年人中的表现可能不典型。随着全球人口老龄化,有效且低风险的诊断策略对于改善患者预后、减少辐射暴露以及降低医疗成本变得越来越重要。这项回顾性队列研究在2020年1月至2024年12月期间进行。我们旨在评估STONE和新STONE评分在检测60岁及以上出现侧腹痛的患者输尿管结石中的诊断性能。总共纳入了161例行腹部计算机断层扫描(CT)的患者,其中48.4%检测到输尿管结石。与无结石患者相比,有结石患者的STONE评分(8.7±2.0对6.1±1.9)和新STONE评分(5.0±1.9对2.7±1.6)显著更高(两者p<0.001)。STONE评分的曲线下面积(AUC)为0.830,新STONE评分为0.829。STONE评分>5时灵敏度为97.4%,而>9时特异性为88.0%。对于新STONE评分,>3时灵敏度为89.7%,>6时特异性为97.6%。两个评分在老年患者中均显示出可靠的诊断准确性。STONE评分更倾向于灵敏度,而新STONE评分更倾向于特异性。我们的研究结果表明,这些评分系统可能有助于影像决策,并有助于减少疑似输尿管结石的老年人不必要的CT暴露和医疗成本。

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本文引用的文献

1
Construction and performance of a clinical prediction rule for ureteral stone without the use of race or ethnicity: A new STONE score.不使用种族或民族信息构建和验证输尿管结石临床预测规则:一种新的STONE评分
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Urological Guidelines for Kidney Stones: Overview and Comprehensive Update.肾结石的泌尿外科指南:概述与全面更新
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Epidemiology of Kidney Stones.肾结石的流行病学
Healthcare (Basel). 2023 Feb 2;11(3):424. doi: 10.3390/healthcare11030424.
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Protein network analysis and functional enrichment via computational biotechnology unravel molecular and pathogenic mechanisms of kidney stone disease.通过计算生物技术进行蛋白质网络分析和功能富集,揭示肾结石病的分子和发病机制。
Biomed J. 2023 Apr;46(2):100577. doi: 10.1016/j.bj.2023.01.001. Epub 2023 Jan 13.
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Use of STONE Score to Predict Urolithiasis in an Asian Emergency Department.使用STONE评分预测亚洲急诊科的尿石症
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Risk factors for kidney stone disease recurrence: a comprehensive meta-analysis.肾结石病复发的风险因素:一项综合荟萃分析。
BMC Urol. 2022 Apr 19;22(1):62. doi: 10.1186/s12894-022-01017-4.
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Cells. 2021 Jul 29;10(8):1926. doi: 10.3390/cells10081926.
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The prospective evaluation of the effectiveness of scoring systems in the emergency department in cases with suspected ureteral stones: STONE? CHOKAI?疑似输尿管结石患者在急诊科应用评分系统的前瞻性评估:STONE?CHOKAI?
Am J Emerg Med. 2021 Nov;49:94-99. doi: 10.1016/j.ajem.2021.05.069. Epub 2021 Jun 1.
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Validity of STONE Score in Clinical Prediction of Ureteral Stone Disease.STONE评分在输尿管结石疾病临床预测中的有效性
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Changing in gender prevalence of nephrolithiasis.肾结石发病率的性别变化。
Urologia. 2021 May;88(2):90-93. doi: 10.1177/0391560320966206. Epub 2020 Oct 21.