PURPOSE

Breast cancer (BC) is the most common cancer occurring during pregnancy. With delayed childbirth, pregnancy-associated breast cancer (PABC) incidence is expected to increase. It can be challenging for mothers undergoing cancer treatment and coping with disease progression to focus on parenting. The child may be affected by the mother's ongoing treatment both prenatally and postnatally. This study aims to investigate the biopsychosocial development of children born to patients with PABC, the emotional stress of patients.

METHODS

This ambispective cohort study combines a retrospective analysis of previously collected data from January 2019 to December 2029 with the prospective recruitment and follow-up of new patients. Patients diagnosed with PABC within the past 5 years will be recruited from hospitals and patient associations. Recruitment and follow-up will occur from July 1, 2024, to December 31, 2029, with 80 participants targeted for both the subject and control groups.

DISCUSSION

This study aims to provide long-term insights into the biopsychological development of children born to PABC patients, as well as the emotional states and QoL. The findings are expected to optimize biopsychosocial development, enhance family well-being, and guide breast cancer patients in making informed pregnancy decisions.

TRIAL REGISTRATION

Clinical Research information Service Identifier: KCT0010225.