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一名12岁女孩的近乎致命性哮喘导致危及生命的扁桃体疝:病例报告

Near-fatal asthma in a 12-year-old girl leading to life-threatening tonsillar herniation: a case report.

作者信息

Almutairi Abdullah, Althobaiti Khalid, Antar Mohannad, Al Alem Hala, Kashgari Amna

机构信息

Department of Pediatrics, King Abdullah Specialist Children's Hospital (KASCH), National Guard Health Affairs (NGHA), Riyadh, Saudi Arabia.

King Abdullah International Medical Research Center (KAIMRC), Ministry of National Guard, Riyadh, Saudi Arabia.

出版信息

J Med Case Rep. 2025 Sep 1;19(1):435. doi: 10.1186/s13256-025-05507-5.

Abstract

BACKGROUND

Severe asthma exacerbations can lead to rare and life-threatening complications such as cerebral edema and tonsillar herniation. This case highlights the importance of early recognition, aggressive treatment, and the implementation of standardized pediatric intensive care unit protocols for managing critical asthma complications.

CASE PRESENTATION

We report the case of a 12-year-old girl of Middle Eastern descent from Saudi Arabia with a history of bronchial asthma and allergic rhinitis who developed cerebral edema and resultant tonsillar herniation following a severe asthma exacerbation. Her presentation was marked by respiratory distress unresponsive to initial therapy. Intensive management in the pediatric intensive care unit including mechanical ventilation and neuroprotective measures resulted in full neurological recovery prior to discharge.

CONCLUSION

This case underscores the need for prompt identification and multidisciplinary management of severe asthma complications in pediatric patients to prevent irreversible outcomes.

摘要

背景

严重哮喘发作可导致罕见且危及生命的并发症,如脑水肿和扁桃体疝。本病例强调了早期识别、积极治疗以及实施标准化儿科重症监护病房方案以管理严重哮喘并发症的重要性。

病例介绍

我们报告了一名来自沙特阿拉伯的12岁中东裔女孩的病例,她有支气管哮喘和过敏性鼻炎病史,在一次严重哮喘发作后出现脑水肿并导致扁桃体疝。她的表现以对初始治疗无反应的呼吸窘迫为特征。在儿科重症监护病房进行的强化管理,包括机械通气和神经保护措施,使她在出院前实现了完全的神经功能恢复。

结论

本病例强调了对儿科患者严重哮喘并发症进行及时识别和多学科管理以预防不可逆后果的必要性。

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