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2024年蛋白质结构预测关键评估(CASP)基础设施的更新。

Updates to the CASP Infrastructure in 2024.

作者信息

Kryshtafovych Andriy, Milostan Maciej, Lensink Marc F, Velankar Sameer, Bonvin Alexandre M J J, Moult John, Fidelis Krzysztof

机构信息

Genome Center, University of California, Davis, Davis, California, USA.

Institute of Computing Science, Poznan University of Technology, Poznan, Poland.

出版信息

Proteins. 2025 Sep 1. doi: 10.1002/prot.70042.

Abstract

CASP (critical assessment of structure prediction) conducts community experiments to determine the state of the art in calculating macromolecular structures. The CASP data management system is continually evolving to address the changing needs of the experiments. For CASP16, we expanded the infrastructure to enable data handling of newly introduced categories and fully support pilot categories introduced in CASP15. This technical note also documents the integration of the CASP and CAPRI (Critical Assessment of PRedicted Interactions) systems.

摘要

蛋白质结构预测关键评估(CASP)开展社区实验以确定计算大分子结构的当前技术水平。CASP数据管理系统在不断发展,以满足实验不断变化的需求。对于CASP16,我们扩展了基础设施,以实现对新引入类别的数据处理,并全面支持CASP15中引入的试点类别。本技术说明还记录了CASP和蛋白质相互作用预测关键评估(CAPRI)系统的整合情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ea/12750030/ec0f521ac889/PROT-94-15-g003.jpg

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