Chai Shuaishuai, Zhou Yuancheng, Dong Manshun, Cheng Gong, Xiang Wei, You Yongqiang, Yu Qiuxuan, Li Ruoyu, Liang Chaoqi, Yuan Jingdong, Xiao Xingyuan, Li Bing
Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Hubei Key Laboratory of Urological Diseases, Wuhan, Hubei, China.
Minerva Urol Nephrol. 2025 Aug;77(4):500-507. doi: 10.23736/S2724-6051.25.06433-X.
The management of long proximal ureteral strictures poses a significant challenge, with traditional options such as renal autotransplantation or bowel interposition associated with substantial morbidity. This study explores the use of robotic ureteroplasty with lingual mucosal graft (RU-LMG) as a minimally invasive approach for treating complex ureteral strictures. We present a multi-institutional cohort to evaluate its effectiveness in managing proximal and mid-ureteral strictures.
This multi-center, retrospective study analyzed perioperative data from 76 patients who underwent RU-LMG at three institutions between January 2021 and December 2023. Patients were selected based on the presence of proximal or mid-ureteral strictures not amenable to primary ureteroureterostomy due to periureteral fibrosis or excessive stricture length. Success was defined as the absence of hydronephrosis, flank pain, or imaging-confirmed obstruction.
Of the 76 patients, 48 (63.2%) underwent onlay ureteroplasty, while 28 (36.8%) received augmented anastomotic RU-LMG. Omental wrapping or coverage of the reconstructed ureter was performed in 73 patients (96.1%). The average length of the stricture and graft were 4.0 cm (range: 2.0-11.5 cm) and 4.1 cm (range: 2.0-12.0 cm), respectively. The mean operative time was 205.5 minutes (range: 95-380 minutes), with a mean blood loss of 70.9 mL (range: 10-400 mL). There were no open conversions or intraoperative complications. The follow-up period ranged from 13 to 48 months (mean: 27 months), with a 100% success rate (76/76 patients).
RU-LMG is a safe, effective, and feasible technique for managing complex proximal or mid-ureteral strictures, with excellent medium-term outcomes and minimal morbidity.
长段近端输尿管狭窄的处理是一项重大挑战,诸如自体肾移植或肠代输尿管术等传统方法会带来较高的发病率。本研究探讨采用带舌黏膜移植的机器人输尿管成形术(RU-LMG)作为治疗复杂性输尿管狭窄的微创方法。我们展示了一个多机构队列,以评估其在处理近端和中段输尿管狭窄方面的有效性。
这项多中心回顾性研究分析了2021年1月至2023年12月期间在三个机构接受RU-LMG的76例患者的围手术期数据。入选患者的标准为存在近端或中段输尿管狭窄,因输尿管周围纤维化或狭窄长度过长而无法进行一期输尿管输尿管吻合术。成功定义为无肾积水、胁腹痛或影像学证实的梗阻。
76例患者中,48例(63.2%)接受了覆盖式输尿管成形术,28例(36.8%)接受了增强吻合的RU-LMG。73例患者(96.1%)进行了大网膜包裹或覆盖重建的输尿管。狭窄段和移植段的平均长度分别为4.0厘米(范围:2.0 - 11.5厘米)和4.1厘米(范围:2.0 - 12.0厘米)。平均手术时间为205.5分钟(范围:95 - 380分钟),平均失血量为70.9毫升(范围:10 - 400毫升)。无中转开放手术或术中并发症。随访期为13至48个月(平均:27个月),成功率为100%(76/76例患者)。
RU-LMG是一种安全、有效且可行的技术,用于处理复杂性近端或中段输尿管狭窄,中期效果良好且发病率极低。