Hagaggi Noura Sh A, Abdul-Raouf Usama M
Botany Department, Faculty of Science, Aswan University, Aswan, 81528, Egypt.
World J Microbiol Biotechnol. 2025 Sep 2;41(9):320. doi: 10.1007/s11274-025-04536-y.
Alkanes are saturated hydrocarbons characterized by their stable chemical properties and multiple uses in the energy sector. Although alkanes are found in nature in various sources like natural gas and petroleum, microbial alkane production has become a promising way to develop sustainable biofuels. Alkanes are produced by microorganisms such as bacteria, fungi, yeast, and algae via particular metabolic pathways. Although progress has been achieved, challenges remain, including low conversion efficiencies and excessive costs of biofuel production compared to conventional fossil fuels, along with the need to enhance microbial resistance to harsh production conditions. By understanding current progress and future challenges, researchers and bioengineers can develop modern technologies and methods to improve the efficiency and effectiveness of microbial alkane production. This review provides a detailed look at the recent developments in microbial biosynthesis of alkanes, highlighting the key metabolic pathways and genetic techniques used to scale up production. It also discusses the challenges and obstacles facing the production of microbial alkanes. The review emphasizes the role of microbial alkane production in promoting a sustainable energy future. This review may enhance awareness of the importance of developing renewable biofuel sources, which supports global efforts to combat climate change and achieve sustainable development.
烷烃是饱和烃，其化学性质稳定，在能源领域有多种用途。尽管烷烃在自然界中存在于天然气和石油等各种来源中，但微生物生产烷烃已成为开发可持续生物燃料的一种有前景的方式。烷烃是由细菌、真菌、酵母和藻类等微生物通过特定的代谢途径产生的。尽管已经取得了进展，但挑战依然存在，包括与传统化石燃料相比生物燃料生产的转化效率低和成本过高，以及需要提高微生物对恶劣生产条件的耐受性。通过了解当前的进展和未来的挑战，研究人员和生物工程师可以开发现代技术和方法，以提高微生物生产烷烃的效率和效果。本综述详细介绍了微生物合成烷烃的最新进展，突出了用于扩大生产规模的关键代谢途径和基因技术。它还讨论了微生物生产烷烃面临的挑战和障碍。该综述强调了微生物生产烷烃在促进可持续能源未来方面的作用。本综述可能会提高人们对开发可再生生物燃料来源重要性的认识，这有助于全球应对气候变化和实现可持续发展的努力。
