Onimus M, Schraub S, Bertin D, Bosset J F, Guidet M
Rev Chir Orthop Reparatrice Appar Mot. 1985;71(7):473-82.
Sixty spinal metastases have been treated surgically. In 22 cases a posterior approach was made with decompression laminectomy and internal fixation. In 38 others an anterior approach was made to resect the vertebral body and replace it by cement. In the thoracic and lumbar spines, internal fixation after a posterior approach led to secondary displacement in five cases out of nine. In contrast, spines approached anteriorly remain stable. The results were analysed after a follow-up period ranging from six months to four years. In most of the cases there was a dramatic improvement in spinal and radicular pain. Twenty-three cases had neurological impairment and in 15 of them this was improved, sometimes with complete recovery. The authors consider that surgery is indicated in metastasis of the vertebral body with collapse of the vertebra and bony compression of the spinal canal. In these cases radiotherapy is relatively ineffective. In contrast the results obtained after surgery in cases with epidural involvement are not better than those obtained by radiotherapy. Surgery should therefore be used only in radioresistant tumours.
60例脊柱转移瘤接受了手术治疗。22例采用后路减压椎板切除术及内固定。另外38例采用前路切除椎体并用骨水泥置换。在胸段和腰段脊柱,9例后路内固定术后有5例出现继发移位。相比之下,前路手术的脊柱保持稳定。随访时间为6个月至4年,之后对结果进行了分析。大多数病例的脊柱和神经根性疼痛有显著改善。23例有神经功能障碍,其中15例有所改善,有时完全恢复。作者认为,椎体转移瘤伴有椎体塌陷及椎管骨质压迫时应行手术治疗。在这些病例中,放疗相对无效。相比之下,硬膜外受累病例手术后的结果并不优于放疗。因此,手术仅应用于放疗抵抗性肿瘤。