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使用“冷热”疗法对支气管内错构瘤进行支气管镜管理——两例患者的初步经验

Bronchoscopic management of endobronchial hamartomas using "hot and cold" therapies - Initial experience in two patients.

作者信息

Chopra Manu, Mishra Gaurav, Tyagi Rahul, Kishore Kislay, Yadav Aseem, Chakrabarti Ritwik, Aggarwal Monika

机构信息

Department of Pulmonary Medicine, AICTS, AFMC Pune, Maharashtra, India.

Department of Radiology, AICTS, AFMC Pune, Maharashtra, India.

出版信息

Lung India. 2025 Sep 1;42(5):456-460. doi: 10.4103/lungindia.lungindia_622_24. Epub 2025 Sep 2.

Abstract

Pulmonary hamartomas are the most common benign tumours of the lung and are often detected incidentally. Endobronchial hamartomas, though rare, can cause significant symptoms such as dyspnoea, haemoptysis, and recurrent respiratory infections due to bronchial obstruction. This report describes the successful bronchoscopic management of symptomatic endobronchial hamartomas in two young Indian males aged 29 and 34 years. Both cases were diagnosed based on radiological and histopathological findings. The first patient underwent eight sessions of electrocautery fulguration using a flexible bronchoscope, while the second was treated with six sessions of cryotherapy delivered through a flexible bronchoscope guided cryoprobe. All procedures were carried out under conscious sedation via nasal insertion of the flexible bronchoscope, with no requirement for rigid bronchoscopy or general anaesthesia. Both patients showed marked symptomatic improvement and near-complete resolution of endobronchial lesions. Follow-up bronchoscopies at 18 and 12 months, respectively, revealed no recurrence, and no procedure-related complications were observed. These cases highlight the safety, efficacy, and minimally invasive nature of flexible bronchoscopic techniques such as electrocautery and cryoablation in managing endobronchial hamartomas, particularly in settings where surgical options may be limited.

摘要

肺错构瘤是肺部最常见的良性肿瘤,常为偶然发现。支气管内错构瘤虽罕见,但可因支气管阻塞导致显著症状,如呼吸困难、咯血和反复呼吸道感染。本报告描述了对两名年龄分别为29岁和34岁的印度年轻男性有症状的支气管内错构瘤成功进行支气管镜治疗的情况。两例均根据影像学和组织病理学检查结果确诊。首例患者使用可弯曲支气管镜进行了8次电灼烧灼治疗,而第二例患者通过可弯曲支气管镜引导的冷冻探头进行了6次冷冻治疗。所有操作均在清醒镇静下经鼻腔插入可弯曲支气管镜完成,无需硬质支气管镜或全身麻醉。两名患者症状均明显改善,支气管内病变几乎完全消退。分别在18个月和12个月时进行的随访支气管镜检查显示无复发,且未观察到与操作相关的并发症。这些病例突出了电灼和冷冻消融等可弯曲支气管镜技术在治疗支气管内错构瘤方面的安全性、有效性和微创性,尤其是在手术选择可能有限的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f239/12453540/3a619a2bc22d/LI-42-456-g001.jpg

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