一例经分子与临床分析确诊的麻疹病毒所致亚急性硬化性全脑炎病例
A Case of Measles Virus-caused Subacute Sclerosing Panencephalitis Diagnosed by Molecular and Clinical Analysis.
作者信息
Liu Tingyan, Zhang Caiyan, Ming Meixiu, Chen Lian, Chen Weiming, Xu Yang, Shen Meili, Liu Jia, Ou Qiuxiang, Bao Hua, Chen Xiangjun, Lu Guoping, Yan Gangfeng
机构信息
Paediatric Intensive Care Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Department of Pathology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
出版信息
Open Forum Infect Dis. 2025 Aug 28;12(8):ofaf453. doi: 10.1093/ofid/ofaf453. eCollection 2025 Aug.
Subacute sclerosing panencephalitis (SSPE) is a rare and lethal neurodegenerative encephalitis caused by persistent measles virus infection. We report an SSPE case in a patient infected at 6 months old, diagnosed using clinical methods and metagenomic sequencing, highlighting the benefits of combining clinical and molecular techniques for improved diagnosis.
亚急性硬化性全脑炎（SSPE）是一种由持续性麻疹病毒感染引起的罕见致命性神经退行性脑炎。我们报告了一例6个月大时感染的SSPE病例，通过临床方法和宏基因组测序进行诊断，突出了结合临床和分子技术以改善诊断的益处。
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