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本文引用的文献

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Clinical Presentation and Spectrum of Gluten Symptomatology in Celiac Disease.乳糜泻中麸质症状的临床表现和谱系。
Gastroenterology. 2024 Jun;167(1):51-63. doi: 10.1053/j.gastro.2024.01.052. Epub 2024 Apr 16.
2
The Effects of Gluten-free Diet on Body Mass Indexes in Adults with Celiac Disease: A Systematic Review and Meta-analysis of Observational Studies.无麸质饮食对乳糜泻成人患者体重指数的影响：一项观察性研究的系统评价和荟萃分析
J Clin Gastroenterol. 2024;58(10):989-997. doi: 10.1097/MCG.0000000000001998. Epub 2024 Mar 27.
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Celiac disease: prevalence, diagnosis, pathogenesis and treatment.乳糜泻：患病率、诊断、发病机制和治疗。
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Atypical celiac disease: from recognizing to managing.非典型乳糜泻：从识别到管理。
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5
Changes in body mass index on a gluten-free diet in coeliac disease: a nationwide study.乳糜泻患者无麸质饮食后体重指数的变化：一项全国性研究。
Eur J Intern Med. 2012 Jun;23(4):384-8. doi: 10.1016/j.ejim.2011.12.012. Epub 2012 Jan 28.
6
Patients with coeliac disease are increasingly overweight or obese on presentation.就诊时，越来越多的乳糜泻患者超重或肥胖。
J Gastrointestin Liver Dis. 2012 Mar;21(1):11-5.
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Am J Med. 2006 Apr;119(4):355.e9-14. doi: 10.1016/j.amjmed.2005.08.044.
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Is obesity an inflammatory condition?肥胖是一种炎症性疾病吗？
Nutrition. 2001 Nov-Dec;17(11-12):953-66. doi: 10.1016/s0899-9007(01)00672-4.
9
Prevalence and clinical presentation of subclinical/silent celiac disease in adults: an analysis on a 12-year observation.成人亚临床/无症状性乳糜泻的患病率及临床表现：一项为期12年观察的分析
Hepatogastroenterology. 2001 Mar-Apr;48(38):462-4.

一名体重指数为50.8kg/m的患者新诊断出乳糜泻。

Newly Diagnosed Celiac Disease in a Patient With a Body Mass Index of 50.8 kg/m.

作者信息

Sachdeva Mehak, Diab Abdul-Rahman, Brown Thomas

机构信息

University of Central Florida College of Medicine/HCA GME Consortium Orlando Florida USA.

HCA Florida Ocala Hospital, Internal Medicine Residency Program Ocala Florida USA.

出版信息

JGH Open. 2025 Aug 29;9(9):e70210. doi: 10.1002/jgh3.70210. eCollection 2025 Sep.

DOI:10.1002/jgh3.70210
PMID:40893424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12395271/
Abstract

Celiac disease (CD) was previously known to be seen in underweight individuals, with weight loss being one of the key symptoms; however, newer data today is starting to show that most adults with celiac disease are either normal weight, overweight or obese. Here we present a 52-year-old patient with a body mass index (BMI) of 50.8 kg/m who was diagnosed with biopsy-proven CD and her tissue transglutaminase immunoglobulin A level was 45.5 U/mL (0-15 U/mL). CD is becoming increasingly prevalent in overweight and obese individuals, making it essential for clinicians to be aware of this atypical presentation to prevent any delay in diagnosis and improve their quality of life.

摘要

乳糜泻（CD）以前被认为多见于体重不足的个体，体重减轻是关键症状之一；然而，如今的新数据开始表明，大多数患有乳糜泻的成年人要么体重正常、超重要么肥胖。在此，我们介绍一位52岁的患者，其体重指数（BMI）为50.8kg/m²，经活检证实患有乳糜泻，其组织转谷氨酰胺酶免疫球蛋白A水平为45.5 U/mL（0 - 15 U/mL）。乳糜泻在超重和肥胖个体中越来越普遍，这使得临床医生必须了解这种非典型表现，以防止诊断延误并改善患者生活质量。