Filiatreau Lindsey M, Szlyk Hannah S, Kasson Erin, Dickson Megan F, Banks Devin, Winograd Rachel, Marotta Phillip, Cavazos-Rehg Patricia
Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Center on Drug and Alcohol Research, University of Kentucky, Lexington, KY, USA.
J Drug Issues. 2025 Jul;55(3):401-419. doi: 10.1177/00220426241229972. Epub 2024 Feb 1.
Medication for opioid use disorder (MOUD) is safe and efficacious for treating opioid use disorder (OUD), yet there is limited understanding of how attitudes and subjective norms regarding MOUD among individuals with OUD may impede treatment uptake. Thus, the current study describes attitudes and subjective norms in a sample of individuals with OUD in the St. Louis area ( = 183) and compares outcomes among those who were and were not actively taking MOUD. Most endorsed positive views regarding pharmacologic treatment for OUD overall, but concerns about physical side effects, the daily nature of some MOUD options, and uncertainty about the relative risks and benefits of MOUD remained prevalent. Individuals reporting current MOUD use had more accepting attitudes and perceived subjective norms regarding MOUD compared to others, suggesting that interventions targeting improvements in the knowledge of, attitudes toward, and normalization of MOUD are needed to further improve uptake and retention in pharmacotherapy for OUD.
用于阿片类物质使用障碍（MOUD）的药物对于治疗阿片类物质使用障碍（OUD）是安全有效的，然而，对于患有OUD的个体对MOUD的态度和主观规范如何可能阻碍治疗的接受度，人们的了解有限。因此，当前的研究描述了圣路易斯地区患有OUD的个体样本（n = 183）的态度和主观规范，并比较了正在积极服用和未服用MOUD的个体之间的结果。总体而言，大多数人对OUD的药物治疗持积极看法，但对身体副作用、某些MOUD选项的日常性质以及MOUD相对风险和益处的不确定性仍然普遍存在。与其他人相比，报告当前正在使用MOUD的个体对MOUD有更接受的态度和感知到的主观规范，这表明需要针对提高对MOUD的认识、态度和使其正常化的干预措施，以进一步提高OUD药物治疗的接受度和持续率。
