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Clinical presentation and symptomatology of Guillain-Barré syndrome: A literature review.格林-巴利综合征的临床表现和症状学:文献复习。
Medicine (Baltimore). 2024 Jul 26;103(30):e38890. doi: 10.1097/MD.0000000000038890.
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Guillain-Barré syndrome: a comprehensive review.格林-巴利综合征:全面综述。
Eur J Neurol. 2024 Aug;31(8):e16365. doi: 10.1111/ene.16365. Epub 2024 May 30.
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Guillain-Barré syndrome: History, pathogenesis, treatment, and future directions.格林-巴利综合征:历史、发病机制、治疗和未来方向。
Eur J Neurol. 2024 Nov;31(11):e16346. doi: 10.1111/ene.16346. Epub 2024 May 16.
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Postpartum Guillain-Barré Syndrome: A Case Report and Literature Review.产后吉兰-巴雷综合征:一例病例报告及文献综述
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Clinical features and maternal and fetal outcomes in women with Guillain-Barré syndrome in pregnancy.妊娠期格林-巴利综合征患者的临床特征及母婴结局。
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Postpartum Guillain-Barré syndrome: a case report.产后吉兰-巴雷综合征:一例报告
Ann Med Surg (Lond). 2023 Feb 6;85(2):191-194. doi: 10.1097/MS9.0000000000000142. eCollection 2023 Feb.
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Guillain-Barré syndrome.格林-巴利综合征。
Lancet. 2021 Mar 27;397(10280):1214-1228. doi: 10.1016/S0140-6736(21)00517-1. Epub 2021 Feb 26.
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Guillain-Barré Syndrome During the Postpartum Period.产后时期的吉兰-巴雷综合征
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Guillain-Barre Syndrome in Postpartum Period: Rehabilitation Issues and Outcome - Three Case Reports.产后吉兰-巴雷综合征:康复问题与结局——三例病例报告
J Neurosci Rural Pract. 2017 Jul-Sep;8(3):475-477. doi: 10.4103/jnrp.jnrp_474_16.
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Guillain-Barré syndrome in pregnancy: A case report.妊娠期格林-巴利综合征:一例报告。
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产后吉兰-巴雷综合征康复:多学科管理与功能结局的病例报告

Postpartum Guillain-Barré Syndrome Rehabilitation: A Case Report on Multidisciplinary Management and Functional Outcomes.

作者信息

Luo Siwan, Zhang Bangkui, Huang Yixuan, Yan Jingwen, Lin Xiaolan, Zhang Xue

机构信息

School of Rehabilitation and Health Care, Guangzhou Health Science College, Guangzhou, Guangdong, People's Republic of China.

Department of Rehabilitation, West China Xiamen Hospital of Sichuan University, Xiamen, Fujian, People's Republic of China.

出版信息

Int Med Case Rep J. 2025 Aug 26;18:1105-1109. doi: 10.2147/IMCRJ.S529582. eCollection 2025.

DOI:10.2147/IMCRJ.S529582
PMID:40893592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12398288/
Abstract

Guillain-Barré syndrome (GBS), a serious acute neurological disorder that can occur during pregnancy and the postpartum period, poses significant risks to maternal health. Severe cases may rapidly progress to generalized paralysis or life-threatening complications, underscoring the urgency of early rehabilitation interventions to mitigate acute sequelae. This report details the rehabilitation journey of a 27-year-old female diagnosed with GBS following cesarean delivery at 36 weeks of gestation. Initially presenting with limb paralysis, respiratory failure, and dysphagia, she received immunoglobulin therapy and mechanical ventilation; however, persistent deficits necessitated transfer to specialized rehabilitation. A multidisciplinary program integrated respiratory training (sputum clearance, high-flow oxygen, speaking valve use), swallowing rehabilitation (oral motor exercises, laryngeal elevation training), physical therapy (joint mobility, electrical stimulation), and psychological support. Following this regimen, she achieved ventilator independence, extended phonation duration from 10 minutes to 1 hour, and demonstrated safer swallowing with reduced aspiration risk. Despite these gains, residual challenges included incomplete limb motor recovery, food spillage due to weak oral musculature, and persistent sensory disturbances. Her progress highlights the role of early multidisciplinary rehabilitation in restoring critical functions in postpartum GBS, while persisting deficits emphasize the need for long-term adaptive care. This case provides actionable insights for optimizing maternal GBS management, advocating integrated care models addressing physical and psychological recovery to advance global maternal health priorities.

摘要

吉兰-巴雷综合征(GBS)是一种严重的急性神经系统疾病,可发生在孕期和产后,对孕产妇健康构成重大风险。严重病例可能迅速发展为全身麻痹或危及生命的并发症,这凸显了早期康复干预以减轻急性后遗症的紧迫性。本报告详细介绍了一名27岁女性的康复历程,该女性在妊娠36周剖宫产术后被诊断为GBS。她最初表现为肢体麻痹、呼吸衰竭和吞咽困难,接受了免疫球蛋白治疗和机械通气;然而,持续的功能缺陷使她需要转至专业康复机构。一个多学科项目整合了呼吸训练(痰液清除、高流量吸氧、使用说话瓣膜)、吞咽康复(口腔运动练习、喉部提升训练)、物理治疗(关节活动度、电刺激)和心理支持。遵循这一治疗方案后,她实现了脱机独立,发声时长从10分钟延长至1小时,吞咽安全性提高,误吸风险降低。尽管取得了这些进展,但仍存在一些遗留挑战,包括肢体运动恢复不完全、口腔肌肉无力导致食物溢出以及持续的感觉障碍。她的康复进展凸显了早期多学科康复在恢复产后GBS关键功能方面的作用,而持续存在的功能缺陷则强调了长期适应性护理的必要性。该病例为优化孕产妇GBS管理提供了可操作的见解,倡导采用综合护理模式来解决身体和心理恢复问题,以推进全球孕产妇健康优先事项。