Stevens Matthew W R, Bertossa Sue, Barry Dominic, Holmwood Chris, Lee Ks Kylie, Marsden John, Pedler Matt, Thompson Mark, Wilson Scott, Ali Robert L
School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia.
Flinders Wellbeing Centre, Salisbury, South Australia, Australia.
Contemp Clin Trials Commun. 2025 Aug 7;47:101532. doi: 10.1016/j.conctc.2025.101532. eCollection 2025 Oct.
Substance use significantly contributes to disease burden among Australians, with harms exacerbated among Aboriginal and Torres Strait Islander peoples by colonisation-related factors like stigma and trauma. Addressing this gap requires culturally acceptable, valid and reliable screening tools, available in a familiar language to the participant, to identify and provide support for those at-risk. This protocol describes a study aimed at validating a culturally-adapted screening tool - the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) - into Pitjantjatjara, to detect risk of substance-related harm.
Recruitment will occur at a variety of Aboriginal health and welfare settings across remote, rural and urban South Australia. Eligible participants (aged 18-65) will be briefed and, upon consent, randomly complete the ASSIST app on an iPad and a semi-structured, yarning-style diagnostic interview (see endnote 1) with a health professional and Pitjantjatjara interpreter. The interview will assess for a range of clinically-defined substance use disorders (based on DSM-5-TR and ICD-11 criteria). All participants will be asked to complete the app a second time (between 7 and 28 days) to assess reliability, while a subset of participants at highest-risk will also undergo specialist evaluation from an independent clinician, as a second check for validity.
Valid and reliable assessment tools are essential for detecting risky and harmful substance use. If valid, this app has the potential to contribute to community-led efforts to bridge the health gap by addressing modifiable health risk factors.
ANZCTR: ACTRN12625000413426. Open Science Framework pre-registration: https://doi.org/10.17605/OSF.IO/GNZAY.
Protocol version 1.1, June 23, 2025.
物质使用对澳大利亚人的疾病负担有重大影响,殖民化相关因素如耻辱感和创伤使原住民和托雷斯海峡岛民所受危害加剧。解决这一差距需要文化上可接受、有效且可靠的筛查工具,以参与者熟悉的语言提供,用于识别有风险的人群并为其提供支持。本方案描述了一项旨在将经过文化调适的筛查工具——酒精、吸烟和物质使用参与度筛查测试(ASSIST)——翻译成皮坚塔加拉语,以检测物质相关伤害风险的研究。
招募工作将在南澳大利亚偏远、农村和城市地区的各种原住民健康和福利机构进行。符合条件的参与者(年龄在18 - 65岁之间)将听取介绍,并在同意后,在iPad上随机完成ASSIST应用程序,并与健康专业人员和皮坚塔加拉语口译员进行一次半结构化的、聊天式诊断访谈(见尾注1)。访谈将评估一系列临床定义的物质使用障碍(基于《精神疾病诊断与统计手册》第5版修订版和《国际疾病分类》第11版标准)。所有参与者将被要求在第二次(7至28天之间)完成该应用程序,以评估可靠性,而一部分风险最高的参与者还将接受独立临床医生的专业评估,作为有效性的第二次检查。
有效且可靠的评估工具对于检测有风险和有害的物质使用至关重要。如果有效,该应用程序有可能通过解决可改变的健康风险因素,为社区主导的缩小健康差距的努力做出贡献。
澳大利亚和新西兰临床试验注册中心:ACTRN12625000413426。开放科学框架预注册:https://doi.org/10.17605/OSF.IO/GNZAY。
方案版本1.1,2025年6月23日。