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一项随机对照试验方案,用于评估为社区中成年自闭症患者量身定制的个性化安置与支持的可行性、可接受性及工作成果。

A randomized controlled trial protocol for evaluating the feasibility, acceptability, and work outcomes of individualized placement and support adapted for autistic adults in the community.

作者信息

Solomon Marjorie, Yon-Hernández Jo A, Ruder Steve, McGurk Susan R, Tancredi Daniel, Takarae Yukari, Stahmer Aubyn C

机构信息

Department of Psychiatry & Behavioral Sciences, MIND Institute, University of California, Davis, USA.

MIND Institute, University of California, Davis, USA.

出版信息

Contemp Clin Trials Commun. 2025 Aug 19;47:101536. doi: 10.1016/j.conctc.2025.101536. eCollection 2025 Oct.

Abstract

Relatively few autistic adults, including those with average intellectual abilities, are competitively employed, meaning that they hold jobs together with non-disabled workers and receive comparable wages and benefits. In California, for example, most autistic individuals served by the state are placed in programs where they participate in skill-building and socialization but not in actual competitive jobs. Failure to participate in the labor force can diminish autistic workers' sense of purpose, well-being, and ability to earn a living wage. Available research suggests that supported employment that assists autistic adults in finding and keeping jobs, produces the highest sustained competitive employment rates. Thus, our team has been investigating the Individualized Placement and Support (IPS) model, which has an extensive evidence base for increasing competitive employment rates in individuals with chronic mental illnesses. In a California Department of Developmental Services Employment Grant investigating adults with autism and intellectual disabilities, we demonstrated a competitive employment placement rate of 52 % using IPS. Components of IPS were appropriate for this population, however there were implementation challenges related to IPS model fit with the vocational support agencies. Based on focus groups and stakeholder input, we have adapted IPS to provide intensive agency training, leadership education, and record keeping support. Herein, we detail a protocol for a randomized controlled trial of the adapted model (IPS-AUT) to evaluate feasibility, acceptability, and work outcomes. We also investigate potential moderators and mediators of treatment effectiveness to provide a foundation for a larger more adequately powered randomized clinical trial. This protocol is registered at ClinicalTrials.gov: NCT06829264.

摘要

相对较少的成年自闭症患者,包括那些智力水平中等的患者,能够获得竞争性就业,也就是说他们与非残疾工人一起工作,并获得可比的工资和福利。例如,在加利福尼亚州,该州服务的大多数自闭症患者都被安排在参与技能培养和社交活动的项目中,而不是从事实际的竞争性工作。未能参与劳动力市场会削弱自闭症患者的目标感、幸福感以及赚取维持生计工资的能力。现有研究表明,支持性就业能够帮助成年自闭症患者找到并保住工作,从而产生最高的持续竞争性就业率。因此,我们的团队一直在研究个性化安置与支持(IPS)模式,该模式在提高慢性精神疾病患者的竞争性就业率方面有广泛的证据基础。在加利福尼亚州发展服务部的一项针对自闭症和智力残疾成年人的就业资助项目中,我们使用IPS模式实现了52%的竞争性就业安置率。IPS模式的组成部分适用于这一人群,然而在将IPS模式与职业支持机构相匹配方面存在实施挑战。基于焦点小组和利益相关者的意见,我们对IPS模式进行了调整,以提供强化的机构培训、领导力教育和记录保存支持。在此,我们详细介绍一种针对调整后的模式(IPS-AUT)的随机对照试验方案,以评估其可行性、可接受性和工作成果。我们还研究治疗效果的潜在调节因素和中介因素,为规模更大、样本量更充足的随机临床试验奠定基础。该方案已在ClinicalTrials.gov上注册:NCT06829264。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cc/12397851/2639d6700890/gr1.jpg

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