Bai Xiaoxuan, Lv Suzhan, Liu Dan, Liu Yuexin, Ping Hao
Department of Urology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Urol Case Rep. 2025 Aug 19;62:103170. doi: 10.1016/j.eucr.2025.103170. eCollection 2025 Sep.
Upper tract urothelial carcinoma in conjunction with congenital renal malformations is exceedingly rare in clinical practice, presenting significant challenges for surgical intervention. We detail a case involving crossed fused renal ectopia accompanied by upper tract urothelial carcinoma. Computed tomography urography imaging revealed abnormalities in the ureteropelvic region. Subsequent urinary cytology, ureteroscopy and pathological analysis confirmed the presence of urothelial carcinoma. A radical laparoscopic nephroureterectomy was conducted, and postoperative pathology indicated a low-grade urothelial carcinoma. No tumor recurrence or metastasis was observed during one-year postoperative follow-up. Our clinical validation confirms laparoscopic surgery as a safe and efficacious therapeutic modality.
上尿路尿路上皮癌合并先天性肾畸形在临床实践中极为罕见，给手术干预带来了重大挑战。我们详细介绍了一例伴有上尿路尿路上皮癌的交叉融合性肾异位病例。计算机断层扫描尿路造影成像显示肾盂输尿管区域存在异常。随后的尿液细胞学检查、输尿管镜检查和病理分析证实存在尿路上皮癌。进行了根治性腹腔镜肾输尿管切除术，术后病理显示为低级别尿路上皮癌。术后一年随访期间未观察到肿瘤复发或转移。我们的临床验证证实腹腔镜手术是一种安全有效的治疗方式。
