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一种更好的方法:使用人工智能工具加速创伤临床指南制定的初始可接受性测试。

A Better Way: Initial Acceptability Testing of Using Artificial Intelligence Tools to Accelerate Development of Trauma Clinical Guidance.

作者信息

Zavala Wong Gabriela, Rosenauer Shannon, Church Chelsea, Sherifali Diana, Racey Megan, Grider Katheryn, Moreno Ashley N, LaGrone Lacey N, Bixby Pamela, Bonne Stephanie, Bulger Eileen M, Cain James G, Chastek Jennifer, Coleman Julia Roberts, Costantini Todd W, Cozzi Nicholas, Davis Kimberly A, Dicker Rochelle A, Dorlac Warren C, Van Eaton Erik, Eriksson Evert, Evans Susan, Foster Shannon Marie, Goodloe Jeffrey M, Haut Elliott R, Jarman Molly, Johnson Alyssa, Kotagal Meera, Krause Morgan, Kubasiak John C, Lang Kelly, Leigh Allison Barbara, Mangat Halinder S, Marvel Debra Marie, Michetti Christopher Paul, Moran Vicki, Moreno Ashley N, Oczkowski Simon Jw, Person Michael A, Price Michelle A, Punch L J, Racey Megan, Ray Bradford L, Redmond Diane, Reinhart Linda Kate, Rhodes Heather, Rhodes Bryn, Rubiano Andres M, Sanchez Sabrina, Sarani Babak, Shelton Erica, Spain David A, Staudenmayer Kristan, Stein Deborah M, Valenzuela Julie, Villarreal Cynthia Lizette, Wells Jeffrey L, Wong Gabriela Zavala, Young LeAnne Sitari

出版信息

medRxiv. 2025 Aug 24:2025.08.20.25334097. doi: 10.1101/2025.08.20.25334097.

Abstract

INTRODUCTION

Representatives of the trauma community have voiced a need for a new approach to developing clinical guidance. In this study, we test the initial acceptability of a proposed 12-step approach that aims to reduce the current clinical guidance timeline from more than 24 months to 24 weeks.

METHODS

Investigators hypothesized that artificial intelligence (AI) tools could be leveraged to improve and make the process of clinical guidance development more efficient, facilitating AI initial output that could later be reviewed by subject matter experts (SMEs). Ensuring ethical standards and a collaborative design. Following the agile methodology, emphasizing continuous delivery and improvement, and the Practical, Robust Implementation and Sustainability Model (PRISM) framework, the investigators drafted a 12-step approach to clinical guidance development in 24 weeks. The process starts with the selection of a clinical topic and culminates in a bedside-ready clinical decision tree.

RESULTS

The 2025 Design conference participants were invited to reflect on this new 12-step approach during two breakout sessions. Participants included a broad range of trauma providers, methodologists, patient representatives, technology, and marketing experts. Their recommendations highlighted: 1) multidisciplinary involvement, 2) need for resource-stratified recommendations, and 3) user-friendly features (offline and multilingual access). On a post conference survey (n=56), 64% were confident in AI accelerating the current development process.

CONCLUSIONS

The current landscape of clinical guidance offers significant opportunities for improvement. Key areas for enhancement include promoting collaboration across multiple disciplines and organizations, developing recommendations that consider resource variations, and utilizing new technologies, such as AI, to expedite the development process. This is crucial because ongoing delays lead to practices lagging behind current evidence. Further research is needed to rigorously test and refine how responsible use of AI can be integrated into expediting evidence integration into clinical guidance.

KEY MESSAGES

Current clinical guidance typically takes 1-2 years to develop. Moreover, clinical guidance may not be published until a year or more after its completion, long after some recommendations become outdated, contributing to lagged evidence-informed practice. This study shares and tests the initial acceptability of a novel approach that aims to reduce the current clinical guidance timeline from 24 months to 24 weeks. It leverages existing artificial intelligence tools but with the critical input of subject matter experts (SMEs), ensuring ethical standards and collaborative design. SMEs shed light on critical steps and key areas that future clinical guidance needs to consider. The current landscape of clinical guidance offers significant opportunities for improvement. Key areas for enhancement include promoting collaboration across multiple disciplines and organizations, developing recommendations that consider resource variations, and utilizing new technologies, such as artificial intelligence, to expedite the development process.

摘要

引言

创伤领域的代表们表示需要一种新的方法来制定临床指南。在本研究中,我们测试了一种提议的12步方法的初步可接受性,该方法旨在将当前临床指南的制定时间从24个月以上缩短至24周。

方法

研究人员假设可以利用人工智能(AI)工具来改进并提高临床指南制定过程的效率,促进人工智能的初步输出,随后由主题专家(SME)进行审查。确保道德标准和协作设计。遵循敏捷方法,强调持续交付和改进,以及实用、稳健实施和可持续性模型(PRISM)框架,研究人员起草了在24周内制定临床指南的12步方法。该过程从选择临床主题开始,最终形成可在床边使用的临床决策树。

结果

邀请了2025设计会议的参与者在两次分组讨论中对这种新的12步方法进行思考。参与者包括广泛的创伤医疗服务提供者、方法学家、患者代表、技术和营销专家。他们的建议强调了:1)多学科参与;2)需要针对不同资源情况分层提出建议;3)用户友好的功能(离线和多语言访问)。在会后调查(n = 56)中,64%的人对人工智能加速当前开发过程充满信心。

结论

当前临床指南的现状提供了显著的改进机会。需要加强的关键领域包括促进多个学科和组织之间的合作,制定考虑资源差异的建议,以及利用人工智能等新技术来加快开发过程。这至关重要,因为持续的延迟导致实践落后于当前证据。需要进一步研究来严格测试和完善如何将负责任地使用人工智能纳入加快将证据整合到临床指南的过程中。

关键信息

当前临床指南的制定通常需要1至2年时间。此外,临床指南可能在完成后一年或更长时间才会发布,此时一些建议早已过时,导致循证实践滞后。本研究分享并测试了一种新方法的初步可接受性,该方法旨在将当前临床指南的制定时间从24个月缩短至24周。它利用现有的人工智能工具,但有主题专家(SME)的关键投入,确保道德标准和协作设计。主题专家阐明了未来临床指南需要考虑的关键步骤和关键领域。当前临床指南的现状提供了显著的改进机会。需要加强的关键领域包括促进多个学科和组织之间的合作,制定考虑资源差异的建议,以及利用人工智能等新技术来加快开发过程。

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