Saxton Aaron, Song David, Wanderling Christopher, Lee Austin, Campbell Timothy, Hassig Stephen, Lee-Saxton Yeon Joo, Jaffe Sarah, Mitchell Kaitlyn, Tapiero Shlomi, Jain Rajat, Quarrier Scott O
Department of Urology, University of Rochester, Rochester, NY, USA.
Department of Surgery, New York Presbyterian-Weill Cornell Medicine, New York, NY, USA.
Curr Urol. 2025 Sep;19(5):343-346. doi: 10.1097/CU9.0000000000000283. Epub 2025 Mar 28.
There is no standard analgesic pathway after percutaneous nephrolithotomy. At our institution, an Enhanced Recovery After Surgery (ERAS) pathway was instated that included a preoperative erector spinae plane (ESP) block to improve pain control and minimize opioid usage in the postoperative setting.
At our institution, an ERAS pathway was created for patients undergoing percutaneous nephrolithotomy. This pathway involved a preoperative ESP block and the replacement of opioids with multimodal analgesia. Patient charts were retrospectively reviewed and placed into 2 cohorts: one cohort participated in the ERAS pathway, whereas the other received traditional pain control. The primary outcome evaluated was postoperative morphine equivalents received. Secondary outcomes included nursing pain scores, opioid prescriptions for home, and quality of life. Descriptive statistics were performed by nonparametric Mann-Whitney and tests for continuous and categorical variables, respectively.
Sixty patients were identified in the ERAS cohort versus 70 in the traditional pain control cohort. There was a statistically significant difference in average postoperative morphine equivalents received (17.0 vs. 39.9, < 0.01) and average postoperative nursing pain score (2.4 vs. 3.6, < 0.01). Fifty-three percent (32/60) of patients in the ERAS cohort received an opioid prescription for home compared with 80% (56/70) in the traditional cohort ( < 0.01). There was no significant quality-of-life difference between the groups. No adverse patient events resulted from the block.
An ERAS pathway including a preoperative ESP block and multimodal analgesia decreased morphine equivalents received and nursing pain scores. Future randomized prospective studies with the ERAS protocol can be considered.
经皮肾镜取石术后尚无标准的镇痛方案。在我们机构,实施了一种术后加速康复(ERAS)方案,其中包括术前竖脊肌平面(ESP)阻滞,以改善疼痛控制并在术后尽量减少阿片类药物的使用。
在我们机构,为接受经皮肾镜取石术的患者制定了ERAS方案。该方案包括术前ESP阻滞以及用多模式镇痛替代阿片类药物。对患者病历进行回顾性审查,并分为两个队列:一个队列采用ERAS方案,另一个队列接受传统的疼痛控制。评估的主要结局是术后接受的吗啡当量。次要结局包括护理疼痛评分、家庭阿片类药物处方以及生活质量。分别采用非参数曼-惠特尼检验和检验对连续变量和分类变量进行描述性统计。
ERAS队列中有60例患者,传统疼痛控制队列中有70例患者。术后接受的平均吗啡当量(17.0对39.9,<0.01)和术后平均护理疼痛评分(2.4对3.6,<0.01)存在统计学显著差异。ERAS队列中53%(32/60)的患者收到了家庭阿片类药物处方,而传统队列中这一比例为80%(56/70)(<0.01)。两组之间的生活质量无显著差异。该阻滞未导致患者出现不良事件。
包括术前ESP阻滞和多模式镇痛的ERAS方案降低了吗啡当量和护理疼痛评分。可考虑未来采用ERAS方案进行随机前瞻性研究。