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脊髓麻醉下经皮肾镜取石术后竖脊肌平面阻滞用于术后镇痛的随机对照研究

Erector spinae plane block for postoperative analgesia following percutaneous nephrolithotomy under spinal anaesthesia- A randomised controlled study.

作者信息

Shah Bhavini, Cherukuri Kaushik, Tudimilla Sonalika, Shah Krusha Suresh

机构信息

Department of Anaesthesiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India.

出版信息

Indian J Anaesth. 2022 Dec;66(12):837-841. doi: 10.4103/ija.ija_692_21. Epub 2022 Dec 20.

Abstract

BACKGROUND AND AIMS

Postoperative pain is a multitude of various irksome sensory, emotional and mental experiences aggravated by surgical trauma and associated with autonomic, endocrine, metabolic, physiological and behavioural responses. The aim of this study was to evaluate the effect of erector spinae plane block (ESPB) in postoperative analgesia following percutaneous nephrolithotomy (PCNL) under spinal anaesthesia.

METHODS

This prospective randomised study was conducted on sixty American Society of Anesthesiologists physical status I and II patients scheduled for PCNL under spinal anaesthesia. They were randomised into two equal groups of thirty patients. ESPB was given in group A with 20 ml of injection bupivacaine 0.25% and dexamethasone 8 mg and group B received injection tramadol 1.5 mg/kg intravenously immediately after PCNL. The primary outcome was comparison of visual analogue scale (VAS) score in the first 24 h postoperatively, whereas secondary objectives included hemodynamic variables and requirement of rescue analgesia.

RESULTS

VAS score in group A (ESPB) with mean of 3.15 ± 0.68 was comparatively low when compared to group B with mean of 6.61 ± 0.50 at 6 hours. After 4 h postoperatively, VAS scores continued to be higher and significant number of patients required rescue analgesia in group B.

CONCLUSION

ESPB reduced VAS score, provided adequate postoperative analgesia, with similar haemodynamic changes and adverse effects in comparison to the conventional analgesia with tramadol in PCNL.

摘要

背景与目的

术后疼痛是由手术创伤加剧的多种令人厌烦的感觉、情绪和心理体验,与自主神经、内分泌、代谢、生理和行为反应相关。本研究的目的是评估竖脊肌平面阻滞(ESPB)在脊髓麻醉下经皮肾镜取石术(PCNL)术后镇痛中的效果。

方法

本前瞻性随机研究对60例计划在脊髓麻醉下进行PCNL的美国麻醉医师协会身体状况I级和II级患者进行。他们被随机分为两组,每组30例患者。A组给予20 ml 0.25%布比卡因和8 mg地塞米松注射液进行ESPB,B组在PCNL后立即静脉注射1.5 mg/kg曲马多注射液。主要结局是术后24小时内视觉模拟量表(VAS)评分的比较,次要目标包括血流动力学变量和补救性镇痛的需求。

结果

A组(ESPB)在6小时时的VAS评分平均为3.15±0.68,与B组平均为6.61±0.50相比相对较低。术后4小时后,B组的VAS评分持续较高,且有相当数量的患者需要补救性镇痛。

结论

与PCNL中使用曲马多的传统镇痛相比,ESPB降低了VAS评分,提供了充分的术后镇痛,且血流动力学变化和不良反应相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd5f/9842086/ceadf9a97957/IJA-66-837-g001.jpg

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