• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

竖脊肌平面阻滞与胸椎硬膜外阻滞对创伤性肋骨骨折患者呼吸、镇痛及血流动力学影响的比较研究

A Comparative Study of Erector Spinae Plane Block and Thoracic Epidural Block on Respiratory, Analgesic, and Hemodynamic Outcomes in Patients With Traumatic Rib Fractures.

作者信息

Kumar Manoj, Singh Rakesh Bahadur, Kumar Atit, Acharya Alankrita

机构信息

Anesthesiology, Uttar Pradesh University of Medical Sciences, Etawah, IND.

Anesthesiology, Autonomous State Medical College, Auraiya, IND.

出版信息

Cureus. 2025 May 17;17(5):e84309. doi: 10.7759/cureus.84309. eCollection 2025 May.

DOI:10.7759/cureus.84309
PMID:40530210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12171276/
Abstract

Background Rib fractures are associated with significant morbidity and mortality. Thoracic epidural analgesia (TEA) provides excellent pain relief in the management of rib fractures. However, side effects, such as hypotension, and the technical challenges associated with its insertion can limit the use of this technique. Erector spinae plane block (ESPB) is a more superficial ultrasound-guided block, which is easier to perform and does not pose the same risk factors. The primary objective of this study was to compare the analgesic efficacy of continuous TEA and continuous ESPB in patients with traumatic rib fractures, measured by pain scores using the visual analog scale (VAS) and mean opioid consumption, expressed in intravenous morphine equivalents (IME). Secondary objectives included evaluating respiratory and hemodynamic parameters and assessing adverse effects. Materials and methods This was a retrospective cohort study including 100 patients aged 18 years or more with a diagnosis of unilateral multiple rib fractures, who received either continuous TEA or continuous thoracic ESPB as a part of their pain management. Patient data were collected from the medical records of individuals admitted to the emergency department. Groups were assigned later based on the analgesic technique received: Group T (TEA) and Group E (ESPB), with interventions performed according to the institutional protocol. Patients in Group T received TEA in the sitting or lateral position using an 18-gauge Tuohy needle, with a 20-gauge epidural catheter placed for continuous infusion. A primary bolus dose of 15 ml bupivacaine 0.125% was administered, followed by continuous infusion at a rate of 0.1 ml/kg/hour for 48 hours. Patients in Group E received ultrasound-guided ESPB using a low-frequency transducer, with a 20-gauge catheter inserted through an 18-gauge Tuohy needle. A bolus dose of 20 ml of bupivacaine 0.125% was given, followed by continuous infusion at a rate of 0.1 ml/kg/hour for 48 hours. Pain scores using VAS, mean opioid consumption, inspiratory peak volumes as measured with an incentive spirometer, and hemodynamic variables (heart rate, mean arterial pressure, and oxygen saturation (SpO2)) were recorded at baseline (0 hours) and at 3, 6, 12, 24, 36, and 48 hours post-procedure. Results The mean VAS scores were comparable between patients who received thoracic epidural analgesia and those who received ESPB across all time points. Additionally, there was no significant difference between the two groups in terms of mean opioid consumption, mean incentive spirometry volumes, and hemodynamic parameters, including heart rate, mean arterial pressure, and oxygen saturation (SpO₂). Conclusion The study concluded that ESPB appears to be a promising alternative to TEA, offering a simpler and safer approach to analgesia in patients with traumatic rib fractures.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7956/12171276/30c46e462e00/cureus-0017-00000084309-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7956/12171276/30c46e462e00/cureus-0017-00000084309-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7956/12171276/30c46e462e00/cureus-0017-00000084309-i01.jpg
摘要

背景

肋骨骨折与显著的发病率和死亡率相关。胸段硬膜外镇痛(TEA)在肋骨骨折的治疗中能提供出色的疼痛缓解。然而,诸如低血压等副作用以及与置管相关的技术挑战可能会限制该技术的应用。竖脊肌平面阻滞(ESPB)是一种更浅表的超声引导下阻滞,操作更简便且不存在相同的风险因素。本研究的主要目的是比较连续TEA和连续ESPB对创伤性肋骨骨折患者的镇痛效果,通过视觉模拟量表(VAS)疼痛评分以及以静脉吗啡当量(IME)表示的平均阿片类药物消耗量来衡量。次要目的包括评估呼吸和血流动力学参数以及评估不良反应。材料与方法:这是一项回顾性队列研究,纳入100例18岁及以上诊断为单侧多发性肋骨骨折的患者,他们接受连续TEA或连续胸段ESPB作为疼痛管理的一部分。患者数据从急诊科收治患者的病历中收集。随后根据所接受的镇痛技术分组:T组(TEA)和E组(ESPB),干预措施按照机构方案进行。T组患者采用18号Tuohy针在坐位或侧卧位接受TEA,置入20号硬膜外导管进行持续输注。给予初始推注剂量15 ml 0.125%布比卡因,随后以0.1 ml/(kg·小时)的速率持续输注48小时。E组患者使用低频探头接受超声引导下ESPB,通过18号Tuohy针插入20号导管。给予20 ml 0.125%布比卡因的推注剂量,随后以0.1 ml/(kg·小时)的速率持续输注48小时。在基线(0小时)以及术后3、6、12、24、36和48小时记录使用VAS的疼痛评分、平均阿片类药物消耗量、用激励肺活量计测量的吸气峰值容积以及血流动力学变量(心率、平均动脉压和血氧饱和度(SpO₂))。结果:在所有时间点,接受胸段硬膜外镇痛的患者与接受ESPB的患者的平均VAS评分相当。此外,两组在平均阿片类药物消耗量、平均激励肺活量计容积以及包括心率、平均动脉压和血氧饱和度(SpO₂)在内的血流动力学参数方面无显著差异。结论:该研究得出结论,ESPB似乎是TEA的一种有前景的替代方法,为创伤性肋骨骨折患者提供了一种更简单、更安全的镇痛方法。

相似文献

1
A Comparative Study of Erector Spinae Plane Block and Thoracic Epidural Block on Respiratory, Analgesic, and Hemodynamic Outcomes in Patients With Traumatic Rib Fractures.竖脊肌平面阻滞与胸椎硬膜外阻滞对创伤性肋骨骨折患者呼吸、镇痛及血流动力学影响的比较研究
Cureus. 2025 May 17;17(5):e84309. doi: 10.7759/cureus.84309. eCollection 2025 May.
2
Regional analgesia techniques for postoperative pain after breast cancer surgery: a network meta-analysis.乳腺癌手术后疼痛的区域镇痛技术:一项网状Meta分析
Cochrane Database Syst Rev. 2025 Jun 4;6(6):CD014818. doi: 10.1002/14651858.CD014818.pub2.
3
Erector spinae plane block versus caudal epidural block in pediatric surgery: a systematic review and meta-analysis of randomized clinical trials.小儿外科中竖脊肌平面阻滞与骶管硬膜外阻滞的比较:一项随机临床试验的系统评价和荟萃分析
Braz J Anesthesiol. 2025 Jul-Aug;75(4):844640. doi: 10.1016/j.bjane.2025.844640. Epub 2025 May 16.
4
Erector spinae plane block with liposomal bupivacaine for post-cesarean analgesia.脂质体布比卡因竖脊肌平面阻滞用于剖宫产术后镇痛
Int J Gynaecol Obstet. 2025 Jul;170(1):489-495. doi: 10.1002/ijgo.70027. Epub 2025 Feb 21.
5
Transversus abdominis plane (TAP) blocks for prevention of postoperative pain in women undergoing laparoscopic and robotic gynaecological surgery.腹横肌平面(TAP)阻滞预防腹腔镜及机器人辅助妇科手术女性患者术后疼痛
Cochrane Database Syst Rev. 2025 Apr 3;4(4):CD015145. doi: 10.1002/14651858.CD015145.pub2.
6
Programmed Intermittent Bolus for Erector Spinae Plane Block Versus Intercostal Nerve Block With Patient-controlled Intravenous Analgesia in Video-assisted Thoracoscopic Surgery: A Randomized Controlled Noninferiority Trial.程序间歇推注竖脊肌平面阻滞与肋间神经阻滞联合患者自控静脉镇痛在电视辅助胸腔镜手术中的比较:一项随机对照非劣效性试验。
Clin J Pain. 2024 Feb 1;40(2):99-104. doi: 10.1097/AJP.0000000000001174.
7
Aural toilet (ear cleaning) for chronic suppurative otitis media.慢性化脓性中耳炎的耳道清理(耳部清洁)
Cochrane Database Syst Rev. 2025 Jun 9;6(6):CD013057. doi: 10.1002/14651858.CD013057.pub3.
8
Comparison of safety and efficacy of thoracic epidural block and erector spinae plane block for analgesia in patients with multiple rib fractures: A pilot single-blinded, randomised controlled trial.胸椎硬膜外阻滞与竖脊肌平面阻滞用于多根肋骨骨折患者镇痛的安全性和有效性比较:一项单盲、随机对照试验的初步研究
Indian J Anaesth. 2023 Jul;67(7):614-619. doi: 10.4103/ija.ija_844_21. Epub 2023 Jul 14.
9
Electronic cigarettes for smoking cessation.用于戒烟的电子烟。
Cochrane Database Syst Rev. 2025 Jan 29;1(1):CD010216. doi: 10.1002/14651858.CD010216.pub9.
10
Erector Spinae Plane Block versus Intercostal Nerve Blocks in Uniportal Videoscopic-assisted Thoracic Surgery: A Multicenter, Double-blind, Prospective Randomized Placebo-controlled Trial.竖脊肌平面阻滞与肋间神经阻滞用于单孔电视胸腔镜手术的比较:一项多中心、双盲、前瞻性随机安慰剂对照试验
Anesthesiology. 2025 Oct 1;143(4):1015-1025. doi: 10.1097/ALN.0000000000005625. Epub 2025 Jun 19.

本文引用的文献

1
Comparison of safety and efficacy of thoracic epidural block and erector spinae plane block for analgesia in patients with multiple rib fractures: A pilot single-blinded, randomised controlled trial.胸椎硬膜外阻滞与竖脊肌平面阻滞用于多根肋骨骨折患者镇痛的安全性和有效性比较:一项单盲、随机对照试验的初步研究
Indian J Anaesth. 2023 Jul;67(7):614-619. doi: 10.4103/ija.ija_844_21. Epub 2023 Jul 14.
2
Comparison of Thoracic Erector Spinae Plane Block With Thoracic Paravertebral Block for Pain Management in Patients With Unilateral Multiple Fractured Ribs.比较单侧多发肋骨骨折患者行胸椎旁神经阻滞与胸椎棘突旁间隙阻滞的镇痛效果。
Pain Physician. 2022 Sep;25(6):483-490.
3
Ultrasound-Guided Fascial Plane Blocks of the Thorax: Pectoral I and II, Serratus Anterior Plane, and Erector Spinae Plane Blocks.
超声引导下胸部筋膜平面阻滞:胸大肌Ⅰ和Ⅱ、前锯肌平面及竖脊肌平面阻滞
Adv Anesth. 2019 Dec;37:187-205. doi: 10.1016/j.aan.2019.08.007. Epub 2019 Sep 13.
4
Novel block and new indication: Ultrasound-guided continuous "mid-point transverse process to pleura" block in a patient with multiple rib fractures.新型阻滞与新适应症:超声引导下对一名多根肋骨骨折患者进行连续“横突中点至胸膜”阻滞
Saudi J Anaesth. 2019 Oct-Dec;13(4):365-367. doi: 10.4103/sja.SJA_773_18.
5
The effect of erector spinae plane block on respiratory and analgesic outcomes in multiple rib fractures: a retrospective cohort study.竖脊肌平面阻滞对多发肋骨骨折患者呼吸和镇痛效果的影响:一项回顾性队列研究。
Anaesthesia. 2019 May;74(5):585-593. doi: 10.1111/anae.14579. Epub 2019 Feb 10.
6
Comparison of continuous thoracic epidural analgesia with bilateral erector spinae plane block for perioperative pain management in cardiac surgery.连续胸段硬膜外镇痛与双侧竖脊肌平面阻滞用于心脏手术围手术期疼痛管理的比较
Ann Card Anaesth. 2018 Jul-Sep;21(3):323-327. doi: 10.4103/aca.ACA_16_18.
7
Erector Spinae Plane Block Versus Retrolaminar Block: A Magnetic Resonance Imaging and Anatomical Study.竖脊肌平面阻滞与椎板间阻滞的比较:一项磁共振成像和解剖学研究。
Reg Anesth Pain Med. 2018 Oct;43(7):756-762. doi: 10.1097/AAP.0000000000000798.
8
Erector spinae plane block may aid weaning from mechanical ventilation in patients with multiple rib fractures: Case report of two cases.竖脊肌平面阻滞可能有助于多根肋骨骨折患者脱机:两例病例报告
Indian J Anaesth. 2018 Feb;62(2):139-141. doi: 10.4103/ija.IJA_599_17.
9
Comparison between continuous thoracic epidural block and continuous thoracic paravertebral block in the management of thoracic trauma.连续胸椎硬膜外阻滞与连续胸椎旁神经阻滞在胸部创伤管理中的比较。
Med J Armed Forces India. 2017 Apr;73(2):146-151. doi: 10.1016/j.mjafi.2016.11.005. Epub 2016 Dec 24.
10
The Conversion Ratio From Intravenous Hydromorphone to Oral Opioids in Cancer Patients.静脉注射氢吗啡酮与口服阿片类药物在癌症患者中的换算比率。
J Pain Symptom Manage. 2017 Sep;54(3):280-288. doi: 10.1016/j.jpainsymman.2017.07.001. Epub 2017 Jul 13.