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竖脊肌平面阻滞与胸椎硬膜外阻滞对创伤性肋骨骨折患者呼吸、镇痛及血流动力学影响的比较研究

A Comparative Study of Erector Spinae Plane Block and Thoracic Epidural Block on Respiratory, Analgesic, and Hemodynamic Outcomes in Patients With Traumatic Rib Fractures.

作者信息

Kumar Manoj, Singh Rakesh Bahadur, Kumar Atit, Acharya Alankrita

机构信息

Anesthesiology, Uttar Pradesh University of Medical Sciences, Etawah, IND.

Anesthesiology, Autonomous State Medical College, Auraiya, IND.

出版信息

Cureus. 2025 May 17;17(5):e84309. doi: 10.7759/cureus.84309. eCollection 2025 May.

Abstract

Background Rib fractures are associated with significant morbidity and mortality. Thoracic epidural analgesia (TEA) provides excellent pain relief in the management of rib fractures. However, side effects, such as hypotension, and the technical challenges associated with its insertion can limit the use of this technique. Erector spinae plane block (ESPB) is a more superficial ultrasound-guided block, which is easier to perform and does not pose the same risk factors. The primary objective of this study was to compare the analgesic efficacy of continuous TEA and continuous ESPB in patients with traumatic rib fractures, measured by pain scores using the visual analog scale (VAS) and mean opioid consumption, expressed in intravenous morphine equivalents (IME). Secondary objectives included evaluating respiratory and hemodynamic parameters and assessing adverse effects. Materials and methods This was a retrospective cohort study including 100 patients aged 18 years or more with a diagnosis of unilateral multiple rib fractures, who received either continuous TEA or continuous thoracic ESPB as a part of their pain management. Patient data were collected from the medical records of individuals admitted to the emergency department. Groups were assigned later based on the analgesic technique received: Group T (TEA) and Group E (ESPB), with interventions performed according to the institutional protocol. Patients in Group T received TEA in the sitting or lateral position using an 18-gauge Tuohy needle, with a 20-gauge epidural catheter placed for continuous infusion. A primary bolus dose of 15 ml bupivacaine 0.125% was administered, followed by continuous infusion at a rate of 0.1 ml/kg/hour for 48 hours. Patients in Group E received ultrasound-guided ESPB using a low-frequency transducer, with a 20-gauge catheter inserted through an 18-gauge Tuohy needle. A bolus dose of 20 ml of bupivacaine 0.125% was given, followed by continuous infusion at a rate of 0.1 ml/kg/hour for 48 hours. Pain scores using VAS, mean opioid consumption, inspiratory peak volumes as measured with an incentive spirometer, and hemodynamic variables (heart rate, mean arterial pressure, and oxygen saturation (SpO2)) were recorded at baseline (0 hours) and at 3, 6, 12, 24, 36, and 48 hours post-procedure. Results The mean VAS scores were comparable between patients who received thoracic epidural analgesia and those who received ESPB across all time points. Additionally, there was no significant difference between the two groups in terms of mean opioid consumption, mean incentive spirometry volumes, and hemodynamic parameters, including heart rate, mean arterial pressure, and oxygen saturation (SpO₂). Conclusion The study concluded that ESPB appears to be a promising alternative to TEA, offering a simpler and safer approach to analgesia in patients with traumatic rib fractures.

摘要

背景

肋骨骨折与显著的发病率和死亡率相关。胸段硬膜外镇痛(TEA)在肋骨骨折的治疗中能提供出色的疼痛缓解。然而,诸如低血压等副作用以及与置管相关的技术挑战可能会限制该技术的应用。竖脊肌平面阻滞(ESPB)是一种更浅表的超声引导下阻滞,操作更简便且不存在相同的风险因素。本研究的主要目的是比较连续TEA和连续ESPB对创伤性肋骨骨折患者的镇痛效果,通过视觉模拟量表(VAS)疼痛评分以及以静脉吗啡当量(IME)表示的平均阿片类药物消耗量来衡量。次要目的包括评估呼吸和血流动力学参数以及评估不良反应。材料与方法:这是一项回顾性队列研究,纳入100例18岁及以上诊断为单侧多发性肋骨骨折的患者,他们接受连续TEA或连续胸段ESPB作为疼痛管理的一部分。患者数据从急诊科收治患者的病历中收集。随后根据所接受的镇痛技术分组:T组(TEA)和E组(ESPB),干预措施按照机构方案进行。T组患者采用18号Tuohy针在坐位或侧卧位接受TEA,置入20号硬膜外导管进行持续输注。给予初始推注剂量15 ml 0.125%布比卡因,随后以0.1 ml/(kg·小时)的速率持续输注48小时。E组患者使用低频探头接受超声引导下ESPB,通过18号Tuohy针插入20号导管。给予20 ml 0.125%布比卡因的推注剂量,随后以0.1 ml/(kg·小时)的速率持续输注48小时。在基线(0小时)以及术后3、6、12、24、36和48小时记录使用VAS的疼痛评分、平均阿片类药物消耗量、用激励肺活量计测量的吸气峰值容积以及血流动力学变量(心率、平均动脉压和血氧饱和度(SpO₂))。结果:在所有时间点,接受胸段硬膜外镇痛的患者与接受ESPB的患者的平均VAS评分相当。此外,两组在平均阿片类药物消耗量、平均激励肺活量计容积以及包括心率、平均动脉压和血氧饱和度(SpO₂)在内的血流动力学参数方面无显著差异。结论:该研究得出结论,ESPB似乎是TEA的一种有前景的替代方法,为创伤性肋骨骨折患者提供了一种更简单、更安全的镇痛方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7956/12171276/30c46e462e00/cureus-0017-00000084309-i01.jpg

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