Narag Jian Carlo R, Cruz Franz Marie O
Department of Ophthalmology and Visual Sciences, Philippine General Hospital, Manila, Philippines.
Department of Ophthalmology and Visual Sciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
Acta Med Philipp. 2025 Jul 31;59(10):119-124. doi: 10.47895/amp.vi0.10696. eCollection 2025.
We report a 39-year-old male who had generalized tonic-clonic seizure with loss of awareness. Investigations led to a diagnosis of a left temporal lobe tumor. He underwent resection of the mass with consequent loss of brain tissue in the temporal lobe and was found to have a complete right homonymous hemianopia in the immediate postoperative period. Macular ganglion cell analysis on optical coherence tomography (OCT) showed homonymous thinning affecting the inferonasal sector in the right eye and inferotemporal sector in the left eye. This case demonstrates transsynaptic retrograde degeneration through the interruption of the inferior optic radiation, and its corresponding effect on the structure and function of the affected retinal field. Temporal lobe lesions may cause not only a homonymous visual field defect contralateral to the side of the lesion but also result to homonymous sectoral thinning of the macular ganglion cell complexes in both eyes located ipsilateral to the side of the lesion.
我们报告了一名39岁男性，他出现了伴有意识丧失的全身强直阵挛性癫痫发作。检查结果诊断为左颞叶肿瘤。他接受了肿块切除术，导致颞叶脑组织缺失，并在术后即刻被发现患有完全性右侧同向性偏盲。光学相干断层扫描（OCT）上的黄斑神经节细胞分析显示，右眼鼻下象限和左眼颞下象限出现同向性变薄。该病例证明了通过下视辐射中断导致的跨突触逆行性变性，以及其对受影响视网膜区域的结构和功能的相应影响。颞叶病变不仅可能导致病变侧对侧的同向性视野缺损，还会导致病变同侧双眼黄斑神经节细胞复合体的同向性扇形变薄。
