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同时性高级别阑尾黏液性肿瘤和腺癌:1例独特病例报告及文献复习

Concurrent high-grade appendiceal mucinous neoplasm and adenocarcinoma: a unique case report and literature review.

作者信息

AlAli Mohammed N, Alnajjar Jawad S, Essa Mohamed S, Alrasheed Arwa F, Alzuhairi Ruba M, Alromaih Nouf A, Amer Sadiq M, Sbaih Mohammed

机构信息

Department of Surgery, Prince Mohammed bin Abdulaziz Hospital, Ministry of Health, Riyadh, Saudi Arabia.

College of Medicine, King Faisal University, Alahsa, Saudi Arabia.

出版信息

J Surg Case Rep. 2025 Aug 29;2025(8):rjaf666. doi: 10.1093/jscr/rjaf666. eCollection 2025 Aug.

DOI:10.1093/jscr/rjaf666
PMID:40894936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12396623/
Abstract

Appendiceal neoplasms (ANs) are rare and often mimic acute appendicitis, complicating timely diagnosis. We report a unique case of a 57-year-old male presenting with right lower quadrant pain, found on imaging to have a ruptured appendiceal mucocele. He underwent open right hemicolectomy, and histopathology revealed concurrent moderately differentiated mucinous adenocarcinoma arising within a high-grade appendiceal mucinous neoplasm-the first such case documented in the literature. This case underscores the need for early detection, proper surgery, and long-term follow-up in managing rare concurrent appendiceal tumors.

摘要

阑尾肿瘤(ANs)较为罕见,常表现类似急性阑尾炎,致使及时诊断复杂化。我们报告了一例独特病例,一名57岁男性因右下象限疼痛就诊,影像学检查发现阑尾黏液囊肿破裂。他接受了开放性右半结肠切除术,组织病理学显示在高级别阑尾黏液性肿瘤内并发中度分化黏液腺癌——这是文献记载的首例此类病例。该病例强调了在处理罕见的并发阑尾肿瘤时早期检测、恰当手术及长期随访的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbf/12396623/56f048c1833f/rjaf666f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbf/12396623/cd1bbac9a49a/rjaf666f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbf/12396623/3466a3e70576/rjaf666f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbf/12396623/56f048c1833f/rjaf666f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbf/12396623/cd1bbac9a49a/rjaf666f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbf/12396623/3466a3e70576/rjaf666f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbf/12396623/56f048c1833f/rjaf666f3.jpg

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本文引用的文献

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Improving appendix cancer prediction with SHAP-based feature engineering for machine learning models: a prediction study.利用基于SHAP的机器学习模型特征工程改进阑尾癌预测:一项预测研究。
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病例报告:阑尾中低级别阑尾黏液性肿瘤与杯状细胞腺癌共存的罕见病例。
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The role of chemotherapy in the treatment of advanced appendiceal cancers: summary of the literature and future directions.化疗在晚期阑尾癌治疗中的作用:文献综述与未来方向
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The American Society of Colon and Rectal Surgeons, Clinical Practice Guidelines for the Management of Appendiceal Neoplasms.美国结肠和直肠外科医师协会,阑尾肿瘤管理临床实践指南。
Dis Colon Rectum. 2019 Dec;62(12):1425-1438. doi: 10.1097/DCR.0000000000001530.
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