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巨大膀胱结石继发膀胱鳞状细胞癌的延迟诊断

Delayed diagnosis of bladder squamous cell carcinoma secondary to massive bladder stone.

作者信息

Chen Wei, Zhou Youfeng, Tang Chunbo, Qin Xiangcheng

机构信息

Department of Urology, Ningbo Yinzhou Second Hospital, Ningbo, China.

出版信息

J Surg Case Rep. 2025 Aug 29;2025(8):rjaf682. doi: 10.1093/jscr/rjaf682. eCollection 2025 Aug.

DOI:10.1093/jscr/rjaf682
PMID:40894938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12394129/
Abstract

A 53-year-old man presented to a local hospital for 4 months with lower back discomfort. Abdominal computed tomography (CT) revealed a 76 × 74 mm bladder stone. He then underwent bladder incision for stone removal and diversion. Post-surgery, the incision became infected and did not heal. Abdominal CT and pelvic magnetic resonance imaging showed thickened bladder walls and soft tissue in the front of the pelvic area. Pathological examination of abdominal wall tissue biopsy indicated moderately differentiated squamous cell carcinoma. He later received chemotherapy along with immunotherapy. Follow-up CT showed no tumor shrinkage and persistent bleeding. Although rare, bladder squamous cell carcinoma secondary to bladder stones requires awareness to avoid delayed diagnosis and improve early treatment.

摘要

一名53岁男性因下背部不适在当地医院就诊4个月。腹部计算机断层扫描(CT)显示有一枚76×74毫米的膀胱结石。随后他接受了膀胱切开取石及改道术。术后,切口感染未愈合。腹部CT和盆腔磁共振成像显示膀胱壁增厚及盆腔前部软组织异常。腹壁组织活检病理检查提示为中分化鳞状细胞癌。他随后接受了化疗及免疫治疗。随访CT显示肿瘤无缩小且持续出血。膀胱结石继发膀胱鳞状细胞癌虽罕见,但需引起重视以避免延误诊断并改善早期治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/aca7043b8471/rjaf682f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/1b7a61362d0a/rjaf682f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/86cb8a578614/rjaf682f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/5025314d985f/rjaf682f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/aca7043b8471/rjaf682f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/1b7a61362d0a/rjaf682f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/86cb8a578614/rjaf682f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/5025314d985f/rjaf682f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ba/12394129/aca7043b8471/rjaf682f4.jpg

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