El-Bolkainy M N, Mokhtar N M, Ghoneim M A, Hussein M H
Cancer. 1981 Dec 15;48(12):2643-8. doi: 10.1002/1097-0142(19811215)48:12<2643::aid-cncr2820481216>3.0.co;2-c.
In a series of 1095 Egyptian patients with carcinoma of the bladder treated by radical cystectomy, 902 cases (82.4%) contained schistosome eggs in the specimens, and 193 (17.6%) were egg-negative. The different tumor parameters were compared in these subgroups to explore any differences that could be related to schistosomal infestation. In egg-positive cases, the tumor developed at a younger age (46.7 years) than in egg-negative cases (53.2 years). Squamous cell carcinoma, commonly of low grade, predominated in the egg-positive group. No difference was observed in the frequency of tumor stages or lymph node metastases between the two subgroups. The limited tendency to distant spread in schistosomal bladder cancer, despite its advanced local stage, is accounted for by the high frequency of low grade tumors rather than the limiting effect of local schistosomal tissue reactions.
在一组1095例接受根治性膀胱切除术治疗的埃及膀胱癌患者中，902例（82.4%）标本中含有血吸虫卵，193例（17.6%）为虫卵阴性。对这些亚组的不同肿瘤参数进行比较，以探讨可能与血吸虫感染相关的差异。在虫卵阳性病例中，肿瘤发病年龄（46.7岁）比虫卵阴性病例（53.2岁）小。虫卵阳性组中以低级别为主的鳞状细胞癌占主导。两组亚组之间在肿瘤分期或淋巴结转移频率方面未观察到差异。血吸虫性膀胱癌尽管局部分期较晚，但远处转移倾向有限，这是由于低级别肿瘤的高频率，而非局部血吸虫组织反应的限制作用。
