Guerrero Yeni Arroyave, Hellal Luis Gerardo García-Herreros, Camacho Julio Cesar Granada
Thoracic Surgery Fellow, Universidad El Bosque, 9th Avenue No. 131A-02, Bogotá 110111, Colombia.
Thoracic Surgery Department, National Cancer Institute, 1st Street No. 9-85, Bogotá 110321, Colombia.
J Surg Case Rep. 2025 Aug 29;2025(8):rjaf559. doi: 10.1093/jscr/rjaf559. eCollection 2025 Aug.
Paraneoplastic neurological syndromes (PNS) are a rare and heterogeneous group of immune-mediated neurological disorders. We report the case of a 32-year-old woman with progressive and severely disabling neurological symptoms. After excluding alternative causes, she was diagnosed with an atypical pulmonary carcinoid tumor. Surgical resection led to partial clinical improvement. This case underscores the importance of considering PNS in patients with unexplained neurological symptoms and highlights the need to investigate for underlying neoplasms as a potential trigger.
副肿瘤性神经系统综合征(PNS)是一组罕见且异质性的免疫介导的神经系统疾病。我们报告了一例32岁女性患者,她出现了进行性且严重致残的神经系统症状。在排除其他可能原因后,她被诊断为非典型肺类癌肿瘤。手术切除后临床症状有部分改善。该病例强调了对于有不明原因神经系统症状的患者考虑PNS的重要性,并突出了对潜在肿瘤作为可能触发因素进行调查的必要性。