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肝脏复发性未分化胚胎性肉瘤伴腹膜和脾脏转移的罕见表现:病例报告及文献复习

A rare presentation of recurrent undifferentiated embryonal sarcoma of the liver with peritoneal and splenic metastases: case report and literature review.

作者信息

Alanbagi Alaa A, Aldarawsha Ali N, Alawad Asdah, Hasan Sora A, Kareem Murtadah R, Ahmed Aula, Al Gehadi Muntadher Y H, Bacha Zaryab, Al-Badri Sajjad G

机构信息

Oncology Department, Warith International Cancer Institute, Karbala, Iraq.

Radiology Department, Warith International Cancer Institute, Karbala, Iraq.

出版信息

J Surg Case Rep. 2025 Aug 30;2025(8):rjaf680. doi: 10.1093/jscr/rjaf680. eCollection 2025 Aug.

Abstract

Undifferentiated embryonal sarcoma of the liver (UESL) is a rare, aggressive pediatric malignancy with a high recurrence rate. We present a case of a 16-year-old male with recurrent UESL and rare peritoneal and splenic metastases. Despite initial complete surgical resection, the tumor recurred, necessitating further surgeries and chemotherapy. PET-CT imaging played a crucial role in monitoring disease progression. This case highlights the importance of a multimodal approach, integrating surgery and systemic therapy, in managing recurrent UESL and underscores the need for long-term surveillance to improve patient outcomes.

摘要

肝未分化胚胎性肉瘤(UESL)是一种罕见的侵袭性儿科恶性肿瘤,复发率高。我们报告一例16岁男性复发性UESL,伴有罕见的腹膜和脾脏转移。尽管最初进行了完整的手术切除,但肿瘤仍复发,需要进一步手术和化疗。PET-CT成像在监测疾病进展中发挥了关键作用。该病例突出了多模式方法(整合手术和全身治疗)在复发性UESL管理中的重要性,并强调了长期监测以改善患者预后的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a80/12398261/41d2fc5c4c3c/rjaf680f1.jpg

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