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倒置内界膜瓣治疗视盘小凹黄斑病变的疗效

Efficacy of inverted internal limiting membrane flap for treating optic disc pit maculopathy.

作者信息

Cheng Anny M S, Paredes Alfredo A, Chalam Kakarla V

机构信息

Department of Ophthalmology, University of Florida, 6201 W Newberry Rd, Gainesville, FL 32605, United States.

Department of Ophthalmology, Florida International University, Herbert Wertheim College of Medicine, 11200 SW 8th St AHC2, Miami, FL 33199, United States.

出版信息

J Surg Case Rep. 2025 Aug 29;2025(8):rjaf678. doi: 10.1093/jscr/rjaf678. eCollection 2025 Aug.

Abstract

Optic disc pit maculopathy is a serious complication of congenital optic disc pits, often resulting in significant vision loss due to intraretinal and subretinal fluid accumulation. This case report describes a 35-year-old woman with progressive visual decline in her right eye. Examination revealed optic disc pit maculopathy with marked central foveal thickness (634 μm) and a best-corrected visual acuity of 20/100. The patient underwent pars plana vitrectomy, induction of posterior vitreous detachment, selective internal limiting membrane peeling to create a temporal flap, inversion of the flap over the optic disc pit, and gas tamponade with 25% sulfur hexafluoride. At 8 months postoperatively, there was complete resolution of retinal fluid, reduction in central foveal thickness to 261 μm, and best-corrected visual acuity improved to 20/20. These anatomical and functional gains were maintained at 16 months, highlighting the efficacy and safety of the inverted ILM flap technique in optic disc pit maculopathy management.

摘要

视盘小凹黄斑病变是先天性视盘小凹的一种严重并发症,常因视网膜内和视网膜下液体积聚导致显著视力丧失。本病例报告描述了一名35岁右眼视力进行性下降的女性。检查发现视盘小凹黄斑病变,中央凹厚度明显增加(634μm),最佳矫正视力为20/100。患者接受了玻璃体切除术、诱导玻璃体后脱离、选择性内界膜剥除以形成颞侧瓣、将瓣翻转覆盖在视盘小凹上,并用25%的六氟化硫进行气体填塞。术后8个月,视网膜下液完全消退,中央凹厚度降至261μm,最佳矫正视力提高到20/20。这些解剖和功能上的改善在16个月时得以维持,突出了倒置内界膜瓣技术在视盘小凹黄斑病变治疗中的有效性和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ae9/12394119/67b05d4ad4c5/rjaf678f1.jpg

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