D'souza Palmeera, Verghese Shishir, Ranjan Ratnesh, Kumarswamy Karan, Saravanan Veerappan R, Manayath George J, Narendran Venkatapathy
Department of Retina and Vitreous, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, IND.
Cureus. 2021 Mar 23;13(3):e14057. doi: 10.7759/cureus.14057.
Purpose To evaluate the anatomical and visual outcomes in optic disc pit maculopathy following pars plana vitrectomy (PPV) with inverted internal limiting membrane (ILM) flap Methods Retrospective interventional case series of 10 patients diagnosed with serous macular detachment secondary to optic disc pit who underwent PPV with inverted ILM flap and were followed up for a year. Results A p-value of less than 0.05 was defined as statistically significant. The mean age of patients was 27.2 ± 10.6 years, preoperatively the mean best-corrected visual acuity of the logarithm of the minimum angle of resolution was 0.91 ± 0.42 (approximate Snellen equivalent 20/162), which improved to the logarithm of the minimum angle of resolution of 0.58 ± 0.29 (approximate Snellen equivalent 20/76) at end of one year, (p=0.008). The mean central macular thickness was 804.9 ± 294.1 m which improved to 273.4 ± 102.54 m, (p=0.002). After surgery, at end of one year, 60% of patients (6/10) had 15- or more-than-15-letter improvement of vision on Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity testing, 20% (2/10) gained a 10-letter improvement and 20% (2/10) retained the same vision. Conclusion PPV with inverted ILM flap can be considered as a good approach for the management of serous macular detachment secondary to optic disc pit and produce good anatomical and visual results at one year with stabilization of the disease.
目的 评估经平坦部玻璃体切除术(PPV)联合内界膜(ILM)反转瓣治疗视盘小凹黄斑病变的解剖学和视觉效果。方法 对10例诊断为视盘小凹继发浆液性黄斑脱离的患者进行回顾性干预病例系列研究,这些患者接受了PPV联合ILM反转瓣手术,并随访1年。结果 p值小于0.05被定义为具有统计学意义。患者的平均年龄为27.2±10.6岁,术前最小分辨角对数的平均最佳矫正视力为0.91±0.42(近似Snellen视力表等效值20/162),在1年末提高到最小分辨角对数的0.58±0.29(近似Snellen视力表等效值20/76),(p = 0.008)。黄斑中心平均厚度为804.9±294.1μm,改善至273.4±102.54μm,(p = 0.002)。术后1年末,60%的患者(6/10)在糖尿病视网膜病变早期治疗研究(ETDRS)视力测试中视力提高了15行或更多,20%(2/10)提高了10行,20%(2/10)视力保持不变。结论 PPV联合ILM反转瓣可被视为治疗视盘小凹继发浆液性黄斑脱离的一种良好方法,1年时可产生良好的解剖学和视觉效果,且病情稳定。