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Cobb角≥100°的重度青少年特发性脊柱侧凸(AIS)患者的围手术期结局:一期后路脊柱融合术联合根治性关节突切除术的可行性

Perioperative outcomes of severe adolescent idiopathic scoliosis (AIS) patients with Cobb angle ≥ 100°: Feasibility of single-staged posterior spinal fusion with radical facetectomies.

作者信息

Chandirasegaran Saturveithan, Goparaju Praveen V N R, Chiu Chee Kidd, Chan Chris Yin Wei, Hasan Mohd Shahnaz, Kwan Mun Keong

机构信息

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.

Care Hospital, Hi-tech City, Hyderabad, Telangana, 500032, India.

出版信息

Brain Spine. 2025 Aug 7;5:104378. doi: 10.1016/j.bas.2025.104378. eCollection 2025.

DOI:10.1016/j.bas.2025.104378
PMID:40895033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12391818/
Abstract

INTRODUCTION

Surgical strategies for severe scoliosis often necessitate extensive approaches and major osteotomies to achieve optimal results. The objective of this study is to assess the perioperative outcomes of severe AIS patients with Cobb angle ≥100° undergoing single-staged posterior spinal fusion (PSF) without major osteotomies and pre-operative halo traction.

RESEARCH QUESTION

Is it feasible to perform a single-stage PSF without major osteotomies for AIS patients with Cobb angle ≥100°?

MATERIAL AND METHODS

Thirty-five severe AIS patients with Cobb angle ≥100° who underwent single-staged PSF without major osteotomies or pre-operative halo traction between 2019 and 2023 in a single tertiary centre were recruited. Outcomes were operation duration, intra-operative blood loss, rate of allogenic blood transfusion, correction rate, length of hospital stay and complication rate.

RESULTS

The mean operation duration was 212.6 ± 67 min. The mean intra-operative blood loss was 1121.3 ± 435.2 mL. 14.3% of patients required allogenic blood transfusion. The average number of fusion levels was 13.2 ± 0.9, and the mean correction rate achieved was 52.6 ± 11.2 %. Total hospital stay was 4.5 ± 0.9 days, and the complication rate was 8.6 %. Two patients developed pleural effusion, while one patient had a superficial surgical site infection.

DISCUSSION AND CONCLUSION

The use of a single-staged PSF with radical facetectomies without major osteotomies is a compelling and feasible surgical strategy for severe AIS patients with Cobb angle ≥100°. This surgical approach not only demonstrates efficacy in achieving satisfactory results but also showcases a notable reduction in the complication rate and a shorter hospital stay.

摘要

引言

重度脊柱侧弯的手术策略通常需要广泛的手术入路和大型截骨术以获得最佳效果。本研究的目的是评估Cobb角≥100°的重度特发性脊柱侧弯(AIS)患者在不进行大型截骨术和术前头环牵引的情况下接受单阶段后路脊柱融合术(PSF)的围手术期结果。

研究问题

对于Cobb角≥100°的AIS患者,不进行大型截骨术而进行单阶段PSF是否可行?

材料与方法

招募了35例Cobb角≥100°的重度AIS患者,这些患者于2019年至2023年在单一三级中心接受了不进行大型截骨术或术前头环牵引的单阶段PSF。结果指标包括手术时间、术中失血量、异体输血率、矫正率、住院时间和并发症发生率。

结果

平均手术时间为212.6±67分钟。平均术中失血量为1121.3±435.2毫升。14.3%的患者需要异体输血。平均融合节段数为13.2±0.9,平均矫正率为52.6±11.2%。总住院时间为4.5±0.9天,并发症发生率为8.6%。2例患者出现胸腔积液,1例患者发生表浅手术部位感染。

讨论与结论

对于Cobb角≥100°的重度AIS患者,采用不进行大型截骨术的单阶段PSF联合根治性关节突切除术是一种有说服力且可行的手术策略。这种手术方法不仅在取得满意效果方面显示出有效性,而且并发症发生率显著降低,住院时间缩短。

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本文引用的文献

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Clin Spine Surg. 2025 Oct 1;38(8):360-367. doi: 10.1097/BSD.0000000000001755. Epub 2025 Jan 3.
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Surgical treatment of severe adolescent idiopathic scoliosis through one-stage posterior-only approach: A systematic review and meta-analysis.通过一期单纯后路手术治疗重度青少年特发性脊柱侧凸:一项系统评价和Meta分析
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Severe Lenke 1 and 2 adolescent idiopathic scoliosis had poorer perioperative outcome, higher complication rate, longer fusion and higher operative cost compared to non-severe scoliosis.与非严重脊柱侧弯相比,严重 Lenke 1 型和 2 型青少年特发性脊柱侧弯患者的围手术期结果较差,并发症发生率较高,融合时间较长,手术费用更高。
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One-stage multiple posterior column osteotomies and fusion and pre-op halo-gravity traction may result in a comparative and safer correction of complex spine deformity than vertebral column resection.一期多节段后柱截骨融合及术前 halo-gravity 牵引可能比脊柱截骨术更能安全有效地矫正复杂脊柱畸形。
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Factors Affecting Length of Stay Following 3-Column Spinal Osteotomies in Pediatric Patients.影响小儿患者三柱脊柱截骨术后住院时间的因素。
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