Aryanian Zeinab, Nikjan Ali, Heidari Sama, Omid Reza, Lajevardi Vahide, Hatami Parvane, Babaie Hanie
Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran Iran.
Department of Dermatology, Razi Hospital Tehran University of Medical Sciences Tehran Iran.
Health Sci Rep. 2025 Aug 28;8(9):e71211. doi: 10.1002/hsr2.71211. eCollection 2025 Sep.
Although the development of acne is influenced by a range of factors, emerging research suggests that dietary choices may also play a role in acne management. The Mediterranean diet is an antioxidant-rich, low-glycemic diet with preventive benefit against a range of chronic illnesses. We aimed to investigate the adherence to Mediterranean diet in acne patients and its association with disease severity.
In this case-control study, 105 patients with acne and 105 control individuals were enrolled and their clinical and demographic characteristics were assessed. A valid Persian version of a 14-item questionnaire called the Mediterranean diet adherence screener (MEDAS) was used to assess adherence to the Mediterranean diet.
We did not find any significant difference regarding adherence to Mediterranean diet between patients and control group ( value = 0.19). 68.6% of male and 54.3% of female patients had low adherence to the Mediterranean diet. There was no significant difference between diet adherence and most of clinical and demographic characteristics of participants including the type of acne, age of onset, gender, disease duration, treatment type, and diet adherence ( > 0.05). A statistical correlation was found between BMI and diet adherence, with < 0.05. Total adherence to the Mediterranean diet among patients was significantly correlated with disease severity ( value = 0.004). We also found significant correlations between disease severity and consumption of some items in the questionnaire including olive oil, butter, nuts and poultry (P values: 0.014, 0.018, 0.005 and 0.018, respectively).
Our results suggest beneficial associations between certain aspects of the Mediterranean diet and milder acne severity. Adherence to this healthy dietary pattern may represent a practical adjuvant approach for acne management.
尽管痤疮的发生受多种因素影响,但新出现的研究表明,饮食选择在痤疮管理中可能也起作用。地中海饮食是一种富含抗氧化剂、低血糖指数的饮食,对一系列慢性疾病具有预防作用。我们旨在调查痤疮患者对地中海饮食的依从性及其与疾病严重程度的关联。
在这项病例对照研究中,招募了105例痤疮患者和105名对照个体,并评估了他们的临床和人口统计学特征。使用一份名为地中海饮食依从性筛查问卷(MEDAS)的14项有效波斯语版本问卷来评估对地中海饮食的依从性。
我们发现患者与对照组在对地中海饮食的依从性方面没有显著差异(值 = 0.19)。68.6%的男性患者和54.3%的女性患者对地中海饮食的依从性较低。饮食依从性与参与者的大多数临床和人口统计学特征(包括痤疮类型、发病年龄、性别、病程、治疗类型和饮食依从性)之间没有显著差异(> 0.05)。发现体重指数(BMI)与饮食依从性之间存在统计学相关性,< 0.05。患者对地中海饮食的总体依从性与疾病严重程度显著相关(值 = 0.004)。我们还发现疾病严重程度与问卷中的一些项目(包括橄榄油、黄油、坚果和家禽)的摄入量之间存在显著相关性(P值分别为0.014、0.018、0.005和0.018)。
我们的结果表明地中海饮食的某些方面与较轻的痤疮严重程度之间存在有益关联。坚持这种健康的饮食模式可能是痤疮管理的一种实用辅助方法。