Ah-Thiane Laurie, Nguyen Jean Michel, Khammari Amir, Dréno Brigitte
Service de Dermatologie, Université de Nantes, CHU Nantes, CRCINA, Nantes, France.
Service de Biostatistiques, PIMES Hôpital St Jacques, CHU Nantes, Nantes, France.
Int J Womens Dermatol. 2022 May 13;8(2):e017. doi: 10.1097/JW9.0000000000000017. eCollection 2022 Jun.
Acne is a common benign inflammatory disease, but it has a significant psychosocial impact. The role of the diet in the development of acne is controversial. Some daily foods such as milk and fast-release sugars tend to promote acne. The Mediterranean Diet (MD) is based on virgin olive oil and nuts that are rich in polyphenols with anti-inflammatory properties. The aim of this study was to assess an association between the adherence to the MD and the severity of facial acne in French women. A case-control observational study was conducted in Nantes Hospital (France). Based on a validated PREvención con DIeta MEDiterránean questionnaire, the adherence to the MD was assessed. The Global Evaluation Acne severity score was assessed by a trained dermatologist. Forty women with mild-to-severe acne and 40 control subjects were included. A global linear model identified a significant negative correlation between the severity of acne and the adherence to the MD in acne patients (regression coefficient = -0.17; = 0.017). This was the first study conducted in France to investigate the relationship between the adherence to the MD and the severity of facial acne in women. This study confirmed the importance of using a holistic approach for acne management. Further studies are needed to confirm our findings.
痤疮是一种常见的良性炎症性疾病，但它具有重大的社会心理影响。饮食在痤疮发病中的作用存在争议。一些日常食物，如牛奶和快速释放的糖类，往往会加重痤疮。地中海饮食（MD）以初榨橄榄油和富含具有抗炎特性的多酚类物质的坚果为基础。本研究的目的是评估法国女性对地中海饮食的依从性与面部痤疮严重程度之间的关联。在法国南特医院进行了一项病例对照观察研究。基于一份经过验证的地中海饮食预防问卷，评估对地中海饮食的依从性。由一名经过培训的皮肤科医生评估全球痤疮严重程度评分。纳入了40名轻至重度痤疮女性患者和40名对照受试者。一个全局线性模型确定了痤疮患者中痤疮严重程度与对地中海饮食的依从性之间存在显著的负相关（回归系数 = -0.17；P = 0.017）。这是在法国进行的第一项研究，旨在调查女性对地中海饮食的依从性与面部痤疮严重程度之间的关系。本研究证实了采用整体方法管理痤疮的重要性。需要进一步的研究来证实我们的发现。
