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人工与机器人辅助全髋关节置换术后的住院时间、疼痛及阿片类药物使用情况

Length of stay, pain and opioid consumption following manual versus robotic-assisted total hip arthroplasty.

作者信息

Oettl Felix C, Weinblatt Aaron I, Lyman Stephen, Wang Shu-Han, Parides Michael, Coxe Francesca, Lee Gwo-Chin, Ranawat Amar S, Gonzalez Della Valle Alejandro

机构信息

Hospital for Special Surgery, New York, NY, USA.

Department of Orthopedic Surgery, Balgrist University Hospital, University of Zürich, Zurich, Switzerland.

出版信息

J Orthop. 2025 Aug 12;70:202-207. doi: 10.1016/j.jor.2025.08.018. eCollection 2025 Dec.

DOI:10.1016/j.jor.2025.08.018
PMID:40895353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12391804/
Abstract

BACKGROUND

Robotic assistance in total hip arthroplasty (THA) has increased, but the influence on outcomes compared to manual THA remains uncertain. With the growing emphasis on reducing opioid consumption after arthroplasty, we studied whether robotic assistance was associated with length of stay (LOS), pain, and opioid use after THA.

MATERIALS AND METHODS

We included 14,501 opioid-naïve patients who underwent THA at a single institution between 2019 and 2023 (8900 manual and 5601 robotic). In-hospital pain scores (NRS), LOS, and opioid consumption patterns were collected. Opioid dosages were converted to morphine milligram equivalents (MMEs). After preliminary bivariate analysis, multivariable linear regression analyses were performed adjusting for age, sex, race, BMI, ASA-class, smoking status, cement use, marital status, year of surgery, surgeon experience, approach and periarticular injection.

RESULTS

Robotic THA was associated with significantly shorter LOS (Estimate: 6.8 h, 95 %CI: 8.0, -5.6, p < 0.0001). Robotic THA patients had higher minimal and mean pain scores (Estimate: 0.03, 95 %CI: 0.02-0.05, p < 0.001; Estimate: 0.08, 95 %CI: 0.03, 0.14, p = 0.0042). Robotic THA patients used less MMEs per hour of hospitalization (Estimate -0.11 MMEs, 95 %CI -0.174, -0.039, p = 0.0021), but were prescribed more MMEs at discharge (Estimate: 3.59 MMEs, 95 %CI: 0.323, 6.856, p = 0.0312). The differences in MMEs refilled after discharge and total 90-day opioid prescription patterns were not significant.

CONCLUSION

Robotic assistance in THA was independently associated with a slightly shorter LOS. The significantly higher pain scores (0.08 points of NRS) and lower in-hospital opioid consumption (0.11 MMEs/hour) suggest that while some statistically significant differences exist between robotic-assisted and manual THA, these differences may not be clinically meaningful.

摘要

背景

全髋关节置换术(THA)中机器人辅助的应用有所增加,但与手动THA相比,其对手术结果的影响仍不确定。随着人们越来越重视减少关节置换术后的阿片类药物消耗,我们研究了机器人辅助是否与THA后的住院时间(LOS)、疼痛及阿片类药物使用有关。

材料与方法

我们纳入了2019年至2023年间在单一机构接受THA的14501例未使用过阿片类药物的患者(8900例手动手术和5601例机器人辅助手术)。收集了住院期间的疼痛评分(NRS)、LOS及阿片类药物消耗模式。阿片类药物剂量换算为吗啡毫克当量(MMEs)。在进行初步双变量分析后,进行多变量线性回归分析,并对年龄、性别、种族、BMI、ASA分级、吸烟状况、骨水泥使用、婚姻状况、手术年份、外科医生经验、手术入路及关节周围注射进行校正。

结果

机器人辅助THA与显著缩短的LOS相关(估计值:6.8小时,95%CI:-8.0,-5.6,p<0.0001)。机器人辅助THA患者的最低和平均疼痛评分更高(估计值:0.03,95%CI:0.02-0.05,p<0.001;估计值:0.08,95%CI:0.03,0.14,p=0.0042)。机器人辅助THA患者每住院小时使用的MMEs更少(估计值-0.11 MMEs,95%CI -0.174,-0.039,p=0.0021),但出院时开具的MMEs更多(估计值:3.59 MMEs,95%CI:0.323,6.856,p=0.0312)。出院后补充的MMEs差异及90天阿片类药物总处方模式差异不显著。

结论

THA中的机器人辅助与略短的LOS独立相关。显著更高的疼痛评分(NRS增加0.08分)和更低的住院期间阿片类药物消耗(0.11 MMEs/小时)表明,虽然机器人辅助THA和手动THA之间存在一些统计学上的显著差异,但这些差异可能没有临床意义。