Nwabueze Cherechi O, Erhus Efe, Sapkota Abhin, Yeon Su Yeon, Almoghrabi Anas
Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.
Public Health, George Washington University, Washington, D.C., USA.
Cureus. 2025 Jul 28;17(7):e88941. doi: 10.7759/cureus.88941. eCollection 2025 Jul.
Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm that can involve multiple organs. Most cases are asymptomatic and detected incidentally, but the clinical course can vary significantly. A 40-year-old man presented with abdominal and chest pain; imaging revealed large hepatic masses along with pulmonary nodules. Histopathological examination confirmed the diagnosis of EHE, with positivity for endothelial markers. Given the extent of the disease, systemic therapy was planned. This case highlights the challenges in diagnosing EHE and underscores the need for an individualized approach to managing this rare tumor.
上皮样血管内皮瘤（EHE）是一种可累及多个器官的罕见血管肿瘤。大多数病例无症状，为偶然发现，但临床病程差异很大。一名40岁男性出现腹痛和胸痛；影像学检查发现肝脏有巨大肿块以及肺部结节。组织病理学检查确诊为EHE，内皮标志物呈阳性。鉴于疾病范围，计划进行全身治疗。该病例凸显了EHE诊断中的挑战，并强调了对这种罕见肿瘤进行个体化管理的必要性。
