Lingamgunta Raaj Pawan Kumar, Gurujala Naga Sai Gouthami, Perumallapalli Abhishek
Internal Medicine, NRI Medical College, Chinakakani, IND.
General Medicine, NRI Medical College, Chinakakani, IND.
Cureus. 2025 Jul 30;17(7):e89038. doi: 10.7759/cureus.89038. eCollection 2025 Jul.
Pulmonary embolism (PE) and deep vein thrombosis (DVT) are well-known lethal complications in autoimmune hemolytic anemia (AIHA). Here, we describe a case of a 45-year-old male patient with AIHA who developed DVT early after glucocorticoid administration. The patient presented with severe anemia, suggesting active hemolysis. Deep vein thrombosis was confirmed within two weeks after glucocorticoid administration, suggesting that both active hemolysis and glucocorticoid administration synergistically contributed to the development of DVT. Clinicians should consider that such synergism may increase the risk of thromboembolism in patients with AIHA, and prophylactic anticoagulants are worth considering in these patients after starting glucocorticoids.
肺栓塞（PE）和深静脉血栓形成（DVT）是自身免疫性溶血性贫血（AIHA）中众所周知的致命并发症。在此，我们描述了一例45岁的AIHA男性患者，其在使用糖皮质激素后早期发生了DVT。该患者表现为严重贫血，提示存在活跃溶血。在使用糖皮质激素后两周内确诊为深静脉血栓形成，提示活跃溶血和糖皮质激素的使用协同促成了DVT的发生。临床医生应考虑到这种协同作用可能会增加AIHA患者发生血栓栓塞的风险，并且在这些患者开始使用糖皮质激素后，预防性抗凝治疗值得考虑。
