Jean Louis Frantz, Nichols Lisa, de la Torre Cristina, Dahourou Anicet G
ICF-Infectious Disease Detection and Surveillance Project of USAID, Rockville, MD, United States.
FHI 360, Washington, DC, United States.
Public Health Rev. 2025 Aug 14;46:1608039. doi: 10.3389/phrs.2025.1608039. eCollection 2025.
Timely detection of infectious disease outbreaks is essential to limit health, social, and economic impacts, yet diagnostic and surveillance gaps persist across Africa. This review applies the 7-1-7 global target framework-detect within 7 days, notify within 1, and respond within 7-to assess strategies for strengthening early detection capacities across African countries.
We conducted a review of peer-reviewed literature, institutional reports, and field evidence published without time span limitations. Key themes were organized around five strategic pillars: diagnostic preparedness, surveillance, workforce development, community engagement, and governance.
Identified bottlenecks include limited diagnostic networks capacity, fragmented surveillance systems, workforce shortages, and underinvestment in digital infrastructure. Promising solutions include diagnostic network optimization, deployment of point-of-care molecular tools, integration of event- and indicator-based surveillance through interoperable platforms, and AI-enabled early warning systems. Field examples from Uganda, Senegal, and Nigeria demonstrate improved timeliness where coordinated investments and multisectoral collaboration have been implemented.
Meeting the 7-1-7 detection target requires integrated, country-owned strategies that align diagnostics, surveillance, workforce, and governance within resilient national health security frameworks, underpinned by sustained domestic investment.
及时发现传染病疫情对于限制其对健康、社会和经济的影响至关重要,但非洲各地在诊断和监测方面仍存在差距。本综述应用7-1-7全球目标框架(在7天内检测到、在1天内通报、在7天内做出应对)来评估加强非洲各国早期检测能力的策略。
我们对无时间跨度限制的同行评议文献、机构报告和实地证据进行了综述。关键主题围绕五个战略支柱展开:诊断准备、监测、劳动力发展、社区参与和治理。
已确定的瓶颈包括诊断网络能力有限、监测系统分散、劳动力短缺以及数字基础设施投资不足。有前景的解决方案包括优化诊断网络、部署即时分子检测工具、通过可互操作平台整合基于事件和指标的监测以及启用人工智能的早期预警系统。来自乌干达、塞内加尔和尼日利亚的实地案例表明,在实施了协调投资和多部门合作的地方,及时性得到了改善。
要实现7-1-7检测目标,需要有综合的、国家自主的战略,在有韧性的国家卫生安全框架内,使诊断、监测、劳动力和治理保持一致,并以持续的国内投资为支撑。