Luo Kaiyuan, Bin Jianfeng, Bian Jun, Wang Haomin, Tang Dai, Yan Maozhao, Ge Hua
Department of Gastrointestinal Surgery, Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, China.
Front Oncol. 2025 Aug 15;15:1652318. doi: 10.3389/fonc.2025.1652318. eCollection 2025.
Gastric leiomyoma is a rare, slow-growing benign tumor originating from the smooth muscle cells of the gastric wall. It is typically asymptomatic and presents insidiously. Due to its clinical and imaging features resembling those of gastrointestinal stromal tumors and other gastric neoplasms, it is often misdiagnosed, leading to unnecessary surgical interventions. This article reports a case of gastric leiomyoma in a 28-year-old male, aiming to explore its diagnosis, differential diagnosis, and treatment strategies, emphasizing the importance of comprehensive preoperative imaging evaluation to provide a reference for clinical practice.
A 28-year-old male underwent gastroscopy due to abdominal pain, which revealed a submucosal protrusion in the gastric fundus. Imaging studies (computed tomography, endoscopic ultrasonography, and magnetic resonance imaging) showed a round-like mass approximately 6.3 cm in diameter in the gastric fundus, with mixed internal echogenicity. The patient underwent laparoscopic resection of the gastric fundus tumor, during which the tumor was completely excised. Postoperative pathological and immunohistochemical results confirmed the diagnosis of gastric leiomyoma. The patient recovered well and was discharged one week after surgery.
The diagnosis of gastric leiomyoma requires a combination of imaging, pathological, and immunohistochemical findings to differentiate it from other gastric tumors such as gastrointestinal stromal tumors. Preoperative comprehensive analysis using computed tomography, magnetic resonance imaging, and endoscopic ultrasonography can improve diagnostic accuracy. For gastric leiomyoma, tumor resection with preservation of the cardia is an ideal surgical approach, ensuring negative margins while reducing postoperative complications (anastomotic stenosis). The successful treatment of this case provides a reference for the diagnosis and surgical management of gastric leiomyoma, contributing to improved patient prognosis and quality of life.
胃平滑肌瘤是一种罕见的、生长缓慢的良性肿瘤,起源于胃壁的平滑肌细胞。它通常无症状,隐匿起病。由于其临床和影像学特征与胃肠道间质瘤及其他胃肿瘤相似,常被误诊,导致不必要的手术干预。本文报道一例28岁男性胃平滑肌瘤病例,旨在探讨其诊断、鉴别诊断及治疗策略,强调术前综合影像学评估的重要性,为临床实践提供参考。
一名28岁男性因腹痛接受胃镜检查,发现胃底有一黏膜下隆起。影像学检查(计算机断层扫描、内镜超声和磁共振成像)显示胃底有一个直径约6.3 cm的圆形肿块,内部回声不均匀。患者接受了腹腔镜胃底肿瘤切除术,术中肿瘤被完整切除。术后病理及免疫组化结果确诊为胃平滑肌瘤。患者恢复良好,术后一周出院。
胃平滑肌瘤的诊断需要结合影像学、病理及免疫组化结果,以与胃肠道间质瘤等其他胃肿瘤相鉴别。术前使用计算机断层扫描、磁共振成像和内镜超声进行综合分析可提高诊断准确性。对于胃平滑肌瘤,保留贲门的肿瘤切除术是理想的手术方法,可确保切缘阴性,同时减少术后并发症(吻合口狭窄)。该病例的成功治疗为胃平滑肌瘤的诊断和手术管理提供了参考,有助于改善患者预后和生活质量。