推动从发现到可及的创新:第七届全球结核病疫苗论坛会议报告(2024年10月8 - 10日,巴西里约热内卢)
Driving innovation from discovery to access: Meeting report of the 7 Global Forum on TB Vaccines (8-10 October 2024, Rio de Janeiro, Brazil).
作者信息
Palmer Shaun, Clark Rebecca A, Connell Bridgette J, Muwanga Vanessa Mwebaza, Coelho Arthur, Ogongo Paul, Young Carly
机构信息
Stichting International Aids Vaccine Initiative, Amsterdam, 1013 NH, The Netherlands.
Stop TB Partnership Working Group on New Vaccines, New York, NY 10004, USA.
出版信息
Gates Open Res. 2025 Aug 27;9:65. doi: 10.12688/gatesopenres.16360.1. eCollection 2025.
We urgently need novel, effective, and accessible vaccines to end tuberculosis (TB) as a public health crisis. The 7th Global Forum on TB Vaccines was convened from 8-10 October 2024 in Rio de Janeiro, Brazil. Under the theme of "Driving innovation from discovery to access," the program covered the breadth of TB vaccine research and development (R&D) through implementation, while underscoring the need for greater innovation and investments to advance development and ensure rapid, affordable, and equitable access. Participants shared the latest research on: approaches to diversify the TB vaccine pipeline, candidates advancing through late-stage trials toward licensure, and efforts to ensure new TB vaccines reach the populations that most need them. The forum provided a platform to learn from diverse experts across the field, including researchers, industry, funders, civil society, and affected communities. Participants examined cross-cutting enablers throughout, including opportunities to establish novel partnership and financing models, enhance open science, optimize R&D practices, and strengthen leadership and engagement with community members and high burden countries alike. In this report, we synthesize key themes and findings from the meeting, highlighting progress and priorities in the TB vaccine field.
我们迫切需要新颖、有效且可及的疫苗,以终结作为公共卫生危机的结核病。第七届全球结核病疫苗论坛于2024年10月8日至10日在巴西里约热内卢召开。会议主题为“推动从发现到可及的创新”,议程涵盖了结核病疫苗研发从实施到应用的各个方面,同时强调需要加大创新和投资力度,以推动研发进程,并确保快速、可负担且公平的可及性。与会者分享了以下方面的最新研究:使结核病疫苗研发产品线多样化的方法、正通过后期试验迈向获批的候选疫苗,以及确保新型结核病疫苗惠及最有需求人群的努力。该论坛提供了一个平台,让来自该领域不同专家,包括研究人员、产业界、资助者、民间社会和受影响社区的人士能够相互学习。与会者自始至终审视了贯穿各领域的推动因素,包括建立新型伙伴关系和融资模式、加强开放科学、优化研发实践,以及加强与社区成员和高负担国家的领导力及互动的机会。在本报告中,我们综合了会议的关键主题和研究结果,突出了结核病疫苗领域的进展和优先事项。
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