Ashkar Laila K, Jamjoom Lamia G
From the Department of Radiology, Faculty of Medicine, King Abdulaziz University; and Department of Diagnostic Radiology, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia.
Saudi Med J. 2025 Sep;46(9):1046-1055. doi: 10.15537/smj.2025.46.9.20250316.
To investigate the relationship between breast arterial calcifications (BAC) detected on mammography and coronary artery calcifications (CAC) identified on chest CT in Saudi women, focusing on prevalence, age-specific patterns, and cardiovascular risk factors.
This cross-sectional study was conducted at a tertiary center in Saudi Arabia using data from hospital electronic medical records of 60 women aged 40-88 years who underwent mammography and chest CT, within the same year during the time period from January 2021 to December 2022. Data on demographics, cardiovascular risk factors, and imaging findings were collected. The association between BAC and CAC was analyzed using chi-square tests and binary logistic regression.
The BAC was detected in 33.3% of the participants, while CAC was present in 21.7%. A significant association was observed between the presence of BAC and CAC (=0.015), with 40.0% of BAC-positive patients showing CAC, compared to only 12.5% of BAC-negative patients. Age was a significant predictor of both BAC and CAC, particularly in the 60-69 age group (=0.031). Traditional risk factors such as hypertension and diabetes did not show significant predictive value for CAC or BAC.
The findings highlight the potential utility of BAC as a non-invasive marker for CAC, particularly in older women. Routine reporting of BAC on mammography could enhance cardiovascular risk stratification in clinical practice.
研究沙特女性乳房X线摄影检测到的乳腺动脉钙化(BAC)与胸部CT识别出的冠状动脉钙化(CAC)之间的关系,重点关注患病率、年龄特异性模式和心血管危险因素。
本横断面研究在沙特阿拉伯的一家三级中心进行,使用了2021年1月至2022年12月期间同一年接受乳房X线摄影和胸部CT检查的60名40-88岁女性的医院电子病历数据。收集了人口统计学、心血管危险因素和影像学检查结果的数据。使用卡方检验和二元逻辑回归分析BAC与CAC之间的关联。
33.3%的参与者检测到BAC,而21.7%存在CAC。观察到BAC和CAC的存在之间存在显著关联(P=0.015),BAC阳性患者中有40.0%显示CAC,而BAC阴性患者中只有12.5%。年龄是BAC和CAC的显著预测因素,特别是在60-69岁年龄组(P=0.031)。高血压和糖尿病等传统危险因素对CAC或BAC没有显著预测价值。
研究结果突出了BAC作为CAC无创标志物的潜在效用,特别是在老年女性中。乳房X线摄影中常规报告BAC可加强临床实践中的心血管风险分层。