Galenok V A, Bondar' I A
Ter Arkh. 1985;57(12):16-9.
A study was made of the mechanisms of leucocyte phagocytic and bactericidal activity with relation to Staph, aureus and the NBT-test in simple and simulated variants in 71 patients with diabetes mellitus. A compensatory elevation of the phagocytic index and the phagocytic number was found in all the patients with a decrease in phagocytosis completion which testified to the internal defects of bactericidal activity which, according to the NBT-test results, consisted in insufficient activity of oxidation enzymes. The stimulated NBT-test showed a decrease in phagocytic potentialities in patients with diabetes mellitus. Phagocytosis defects in type I and type II diabetes mellitus were more noticeable in a severe and labile course of the disease.
对71例糖尿病患者进行了研究,观察其白细胞吞噬和杀菌活性机制与金黄色葡萄球菌及NBT试验在单纯和模拟变体中的关系。发现所有患者吞噬指数和吞噬数均有代偿性升高,但吞噬作用完成率下降,这证明杀菌活性存在内在缺陷,根据NBT试验结果,这种缺陷在于氧化酶活性不足。刺激后的NBT试验显示糖尿病患者的吞噬潜力下降。I型和II型糖尿病患者的吞噬缺陷在疾病的严重和不稳定病程中更为明显。