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比较经验丰富的泌尿外科医生与新手泌尿外科医生进行前列腺尿道悬吊术的临床结果和学习曲线。

Comparing the clinical outcomes and learning curves of prostatic urethral lift performed by experienced versus naïve urologists.

作者信息

Hsieh Tsung-Yi, Hong Jian-Hua, Chueh Jeff Shih-Chieh

机构信息

Department of Urology, National Taiwan University Hospital, 7 Chung Shan South Road, Taipei, 10002, Taiwan (R.O.C.).

出版信息

World J Urol. 2025 Sep 2;43(1):532. doi: 10.1007/s00345-025-05895-9.

DOI:10.1007/s00345-025-05895-9
PMID:40897946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12405030/
Abstract

PURPOSE

To characterize the learning process by comparing the clinical outcomes and learning curves of prostatic urethral lift (PUL) performed by experienced versus naïve urologists.

METHODS

Consecutive patients treated with PUL at a tertiary center by an experienced urologist with > 100 PUL cases or by naïve urologists with no prior PUL experience were included in this study. Perioperative parameters, functional outcomes, complications, and retreatment rates were compared. Learning curves were assessed using the cumulative sum (CUSUM) methodology. Multivariate regression identified predictors of operative time.

RESULTS

The median operative time was 20.0 min in both groups. Overall, the International Prostate Symptoms Score total decreased by a median of 9.0 points, quality of life score decreased by a median of 2.0 points, peak urinary flow rate increased by a median of 4.3 ml/sec, and post-void residual volume decreased by a median of 19.8 ml. There were no significant differences between the two groups in functional outcomes, complication rate, or operative time. CUSUM analysis revealed a three-phase learning curve, with proficiency achieved after 5 to 8 cases. Operative time was independently associated with obstructive median lobe (P = 0.003), number of implants (P = 0.005), implant deployment failure (P < 0.001), and experience (P = 0.024).

CONCLUSION

PUL can be safely and effectively performed by both experienced and naïve urologists with comparable outcomes. The learning curve is short but defined with proficiency achieved after 5 to 8 cases.

摘要

目的

通过比较经验丰富的泌尿外科医生与新手泌尿外科医生进行前列腺尿道悬吊术(PUL)的临床结果和学习曲线,来描述学习过程。

方法

本研究纳入了在三级中心接受PUL治疗的连续患者,这些患者由一位有超过100例PUL手术经验的经验丰富的泌尿外科医生或由没有PUL经验的新手泌尿外科医生进行治疗。比较围手术期参数、功能结果、并发症和再治疗率。使用累积和(CUSUM)方法评估学习曲线。多变量回归确定手术时间的预测因素。

结果

两组的中位手术时间均为20.0分钟。总体而言,国际前列腺症状评分总分中位数下降了9.0分,生活质量评分中位数下降了2.0分,最大尿流率中位数增加了4.3毫升/秒,排尿后残余尿量中位数减少了19.8毫升。两组在功能结果、并发症发生率或手术时间方面无显著差异。CUSUM分析显示出一个三阶段的学习曲线,在5至8例手术后达到熟练水平。手术时间与梗阻性中叶(P = 0.003)、植入物数量(P = 0.005)、植入物部署失败(P < 0.001)和经验(P = 0.024)独立相关。

结论

经验丰富的和新手泌尿外科医生都可以安全有效地进行PUL,且结果相当。学习曲线较短,但在5至8例手术后达到熟练水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46d3/12405030/3d52e57c6bc5/345_2025_5895_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46d3/12405030/3d52e57c6bc5/345_2025_5895_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46d3/12405030/3d52e57c6bc5/345_2025_5895_Fig1_HTML.jpg

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