Zhang Xuemei, Zhou Xiaojing, Ding Hongna, Wen Chengcheng, Zhang Lin
Department of Obstetrics and Gynecology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Department of Obstetrics and Gynecology, The CangZhou Central Hospital, Cangzhou, China.
Ann Med Surg (Lond). 2025 May 26;87(9):6041-6044. doi: 10.1097/MS9.0000000000003387. eCollection 2025 Sep.
Heterotopic pregnancy (HP), defined as the coexistence of intrauterine and ectopic pregnancies, is a rare occurrence following natural conception or assisted reproductive technology (ART) procedures. Diagnosing HP can be challenging due to its rarity and often asymptomatic presentation.
We present a case of HP in a woman with unexplained infertility who underwent in vitro fertilization-embryo transfer (IVF-ET). The HP involved an intrauterine pregnancy and a tubal-ovarian pregnancy (OP), which was diagnosed through combined sonography and managed conservatively via laparoscopy.
The incidence of HP is rare, with reported incidences ranging from 1 in 10,000 to 1 in 50,000 naturally conceived pregnancies. Early detection of HP after ART is crucial for preserving intrauterine pregnancies and fertility potential, highlighting the importance of improved sonography imaging techniques.
This case underscores the importance of vigilant monitoring for gynecologists treating IVF patients, not only regarding intrauterine pregnancies but also pregnancies of unknown location. Early and regular ultrasound monitoring, along with expertise in sonography, is essential for accurate diagnosis.
异位妊娠(HP)定义为宫内妊娠和异位妊娠同时存在,在自然受孕或辅助生殖技术(ART)操作后较为罕见。由于其罕见性且常无明显症状,诊断HP具有挑战性。
我们报告一例接受体外受精-胚胎移植(IVF-ET)的不明原因不孕症女性发生HP的病例。该HP包括宫内妊娠和输卵管-卵巢妊娠(OP),通过联合超声检查诊断,并经腹腔镜保守治疗。
HP的发生率很低,自然受孕妊娠的报告发生率为万分之一至五万分之一。ART后早期发现HP对于保留宫内妊娠和生育潜能至关重要,这凸显了改进超声成像技术的重要性。
该病例强调了妇科医生对接受IVF治疗患者进行密切监测的重要性,不仅要关注宫内妊娠,还要关注位置不明的妊娠。早期定期超声监测以及超声检查专业知识对于准确诊断至关重要。