Bhattarai Navin, Dhakal Prasesh, Bhandari Devendra, Katwal Srijana, Bhandari Shristi, Shrestha Shilu
Department of Orthopedics, National Trauma Center, Kathmandu, Nepal.
Department of Internal Medicine, Manmohan Memorial Medical College and Teaching Hospital, Kathmandu, Nepal.
Ann Med Surg (Lond). 2025 Aug 3;87(9):6197-6200. doi: 10.1097/MS9.0000000000003674. eCollection 2025 Sep.
Snakebites, recognized as a neglected tropical disease by the WHO, cause significant morbidity and mortality globally. Although antivenom is the primary treatment, managing complications like compartment syndrome (CS) and soft tissue necrosis remains challenging. This case report describes a 39-year-old woman who developed CS following a green pit viper bite and subsequent antivenom administration, necessitating a fasciotomy.
The patient sustained a bite to her right middle finger, receiving 10 vials of polyvalent anti-snake venom. The next day, she developed symptoms suggestive of CS, prompting an emergency fasciotomy. The procedure included volar and dorsal forearm releases, finger incisions, and compartment releases. She was discharged on day 20 with optimal hand function and instructed to continue physiotherapy.
Snake venom contains toxic peptides and proteases that cause local and systemic effects, with severity influenced by venom quantity, bite location, and timely intervention. Upper extremity bites, particularly to the hand, are prone to CS due to the region's vascularity and anatomy. Although CS after snakebites is rare, its symptoms can mimic local envenomation, requiring careful differentiation and urgent management to prevent permanent damage. Fasciotomy may be necessary if CS persists despite antivenom therapy, as demonstrated in our case.
Snakebites, particularly to the upper extremities, require careful monitoring for complications like CS. Timely diagnosis and fasciotomy are crucial to prevent limb loss and preserve function.
蛇咬伤被世界卫生组织认定为一种被忽视的热带病,在全球范围内导致显著的发病率和死亡率。尽管抗蛇毒血清是主要治疗方法,但处理诸如骨筋膜室综合征(CS)和软组织坏死等并发症仍然具有挑战性。本病例报告描述了一名39岁女性,她在被竹叶青蛇咬伤并随后注射抗蛇毒血清后发生了CS,需要进行筋膜切开术。
患者右手中指被咬伤,接受了10瓶多价抗蛇毒血清治疗。第二天,她出现了提示CS的症状,促使进行紧急筋膜切开术。该手术包括掌侧和背侧前臂切开、手指切开以及骨筋膜室切开。她在第20天出院,手部功能最佳,并被指示继续进行物理治疗。
蛇毒含有导致局部和全身效应的有毒肽和蛋白酶,其严重程度受毒液量、咬伤部位和及时干预的影响。上肢咬伤,尤其是手部咬伤,由于该区域的血管分布和解剖结构,容易发生CS。尽管蛇咬伤后发生CS很罕见,但其症状可能与局部中毒相似,需要仔细鉴别并进行紧急处理以防止永久性损伤。正如我们的病例所示,如果尽管进行了抗蛇毒血清治疗CS仍持续存在,可能需要进行筋膜切开术。
蛇咬伤,尤其是上肢咬伤,需要仔细监测诸如CS等并发症。及时诊断和筋膜切开术对于防止肢体丧失和保留功能至关重要。