Ponsoni Adriana, Sardeli Amanda Veiga, Costa Flavia Pereira, Mourão Lucia Figueiredo
Gerontology program, Faculty of Medical Sciences, University of Campinas - UNICAMP, Campinas, Brazil.
Gerontology program, Faculty of Medical Sciences, University of Campinas - UNICAMP, Campinas, Brazil; Laboratory of Exercise Physiology - FISEX, University of Campinas - UNICAMP, Campinas, Brazil; Institute of Inflammageing and Ageing, University of Birmingham, Birmingham, UK.
Geriatr Nurs. 2023 Jan-Feb;49:44-49. doi: 10.1016/j.gerinurse.2022.11.006. Epub 2022 Nov 19.
We meta-analysed the sarcopenia prevalence among patients with Parkinson´s disease (PD) in comparison to a control group and tested the effects of age, sex, sarcopenia assessments, and PD progression in the sarcopenia prevalence. The literature search was performed using five databases in March 2022. The prevalence of sarcopenia in patients with PD was 3 times higher than in the control group (OR 3.98). Subgroup analyses showed that among individuals aged ≥ 70 years the higher prevalence of sarcopenia in PD compared to controls (OR 5.32, P=0.08) tended to be higher (P=0.08) than the group < 70 years. Regarding PD progression, the prevalence of sarcopenia was not different between individuals scoring < 2.5 and ≥ 2.5 in the Hoehn and Yahr scale. Patients with PD have a higher probability of developing sarcopenia when compared with the control group and older PD patients trended to have even higher chance of sarcopenia than their older controls.
我们对帕金森病(PD)患者与对照组相比的肌肉减少症患病率进行了荟萃分析,并测试了年龄、性别、肌肉减少症评估以及PD进展对肌肉减少症患病率的影响。2022年3月使用五个数据库进行了文献检索。PD患者的肌肉减少症患病率比对照组高3倍(OR 3.98)。亚组分析表明,在≥70岁的个体中,PD患者的肌肉减少症患病率高于对照组(OR 5.32,P=0.08),与<70岁组相比有升高趋势(P=0.08)。关于PD进展,在Hoehn和Yahr量表评分<2.5分与≥2.5分的个体中,肌肉减少症患病率无差异。与对照组相比,PD患者发生肌肉减少症的可能性更高,老年PD患者发生肌肉减少症的几率比老年对照组甚至有更高的趋势。