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IgA肾病相关性高血压视网膜病变和类Purtscher视网膜病变

IgA Nephropathy Associated Hypertensive Retinopathy and Purtscher-Like Retinopathy.

作者信息

Çevik Taha Salim, Kocaman Ata Sena, Özdamar Erol Yasemin, Eser Eylem Pınar

机构信息

Department of Ophthalmology, Ankara Etlik City Hospital, Ankara, Turkey.

Department of Pathology, Ankara Etlik City Hospital, Ankara, Turkey.

出版信息

J Vitreoretin Dis. 2025 Aug 31:24741264251366409. doi: 10.1177/24741264251366409.

Abstract

Purtscher-like retinopathy is a condition similar to Purtscher's retinopathy but results from non-traumatic causes. Although its pathophysiology is not fully understood, it is thought to be related to the complement system. Renal diseases, which play a significant role in secondary hypertension, are known to be important in its etiology. Observational case report. A 22-year-old male patient initially presented with vision-related findings, including both hypertensive retinopathy and Purtscher-like retinopathy, and on further investigation was diagnosed with IgA nephropathy with C3 immunocomplexes, a combination of poor prognostic factors, and rapidly progressive glomerulonephritis. The presence of both hypertensive retinopathy and Purtscher-like retinopathy in our patient indicates an advanced stage of ocular involvement. This emphasizes the critical role of ocular findings in the differential diagnosis and severity of systemic diseases.

摘要

类Purtscher视网膜病变是一种与Purtscher视网膜病变相似但由非创伤性原因引起的病症。尽管其病理生理学尚未完全了解,但据认为与补体系统有关。已知在继发性高血压中起重要作用的肾脏疾病在其病因中很重要。观察性病例报告。一名22岁男性患者最初出现与视力相关的表现,包括高血压性视网膜病变和类Purtscher视网膜病变,进一步检查后被诊断为IgA肾病伴C3免疫复合物,这是一组不良预后因素,以及快速进展性肾小球肾炎。我们的患者同时存在高血压性视网膜病变和类Purtscher视网膜病变,表明眼部受累处于晚期。这强调了眼部表现在全身疾病鉴别诊断和严重程度中的关键作用。

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