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优化痴呆症住院患者安全性的人工智能方法。

Artificial intelligence approach to optimise safety for hospitalised patients with dementia.

作者信息

Bangerter Lauren, Fong Allan, Zabala Garrett, Kim Yijung K, Tabaie Azade, Werner Nicole E, De Jonge Karl Eric, Ratwani Raj M

机构信息

Health Economics and Aging Research (HEAR) Institute, Medstar Health Research Institute, Columbia, MD, USA

Center for Biostatistics, Informatics and Data Science, MedStar Health Research Institute, Columbia, MD, USA.

出版信息

BMJ Open Qual. 2025 Sep 3;14(3):e003270. doi: 10.1136/bmjoq-2024-003270.

Abstract

BACKGROUND

The aim of the study is to develop a machine learning (ML) model to identify contributing factors to dementia-related safety events using patient safety event report data.

METHOD

This study uses dementia-related safety event reports from a patient safety reporting system of a 10-hospital health system in the USA. Contributing factors to safety events were coded using the Yorkshire contributory factors framework based on free-text descriptions in the reports. The coded event reports were used to develop two ML models using eXtreme Gradient Boosting (XGBoost), one to classify situational patient factors and another to classify active failures relating to human error.

RESULTS

We used 1387 safety event reports for model development, 989 (71.3%) reports related to situational factors and 119 (8.6%) reports related to active failures. The model for situational factors achieved a precision of 0.843 and a recall of 0.826. The F1 score was 0.834, indicating a balance of precision and recall performance. The specificity of the model was 0.639 and the area under the receiver operating characteristic curve (ROC AUC) was 0.833. The final model for active failure achieved a precision of 0.333 and a recall of 0.056. The F1 score was 0.095, reflective of imbalanced precision and recall performance. The specificity of the model was 0.992, indicating a strong ability to identify negative cases, and the ROC AUC was 0.817.

CONCLUSION

ML techniques can provide insights into situational factors and active failures that drive dementia-related safety events. These insights can inform targeted interventions such as specialised staff training for behavioural symptoms management and pharmacist-led medication optimisation, to enhance care and safety for hospitalised people living with dementia.

摘要

背景

本研究的目的是开发一种机器学习(ML)模型,利用患者安全事件报告数据来识别导致痴呆相关安全事件的因素。

方法

本研究使用了美国一个拥有10家医院的医疗系统的患者安全报告系统中与痴呆相关的安全事件报告。根据报告中的自由文本描述,使用约克郡促成因素框架对安全事件的促成因素进行编码。编码后的事件报告被用于使用极端梯度提升(XGBoost)开发两个ML模型,一个用于对患者情境因素进行分类,另一个用于对与人为错误相关的主动失误进行分类。

结果

我们使用了1387份安全事件报告进行模型开发,其中989份(71.3%)报告与情境因素相关,119份(8.6%)报告与主动失误相关。情境因素模型的精确率为0.843,召回率为0.826。F1分数为0.834,表明精确率和召回率表现较为平衡。该模型的特异性为0.639,受试者工作特征曲线下面积(ROC AUC)为0.833。主动失误的最终模型精确率为0.333,召回率为0.056。F1分数为0.095,反映出精确率和召回率表现不平衡。该模型的特异性为0.992,表明具有很强的识别阴性病例的能力,ROC AUC为0.817。

结论

ML技术可以深入了解导致痴呆相关安全事件的情境因素和主动失误。这些见解可为针对性干预措施提供参考,如针对行为症状管理的专门人员培训以及药剂师主导的药物优化,以提高痴呆住院患者的护理质量和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f88f/12414173/5b79cfa67057/bmjoq-14-3-g001.jpg

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