Wechsung Katja, Neumann Uta, Balint Nicole, Wiegand Susanna
SPZ Interdisziplinär, Pädiatrische Endokrinologie und Diabetologie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Klinik für pädiatrische Endokrinologie und Diabetologie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Geburtshilfe Frauenheilkd. 2025 Aug 1;85(9):927-933. doi: 10.1055/a-2622-6321. eCollection 2025 Sep.
For up to eight years after menarche, adolescents are in a developmental stage where PCOS (polycystic ovary syndrome) symptoms are physiological. The diagnostic criteria for PCOS in adult women therefore only partially apply. A new German S2k guideline and the international PCOS guideline of 2023 provide standardized diagnostic criteria for hyperandrogenemia and menstrual disorders in adolescence. The provisional diagnosis of PCOS at risk has been introduced for adolescents who only partially meet the criteria and this diagnosis must be revisited three and eight years after menarche. Recommendations for therapy focus on providing information and lifestyle advice to adolescents and on the prevention and treatment of possible comorbidities such as obesity, insulin resistance and hypertension. This paper presents an overview of a structured diagnostic workup and therapeutic approaches to support adolescents with PCOS.
初潮后的长达八年时间里,青少年处于一个多囊卵巢综合征(PCOS)症状属于生理性的发育阶段。因此,成年女性PCOS的诊断标准仅部分适用。德国新的S2k指南和2023年国际PCOS指南为青少年高雄激素血症和月经紊乱提供了标准化诊断标准。对于仅部分符合标准的青少年引入了PCOS风险的临时诊断,且该诊断必须在初潮后三年和八年重新评估。治疗建议侧重于为青少年提供信息和生活方式建议,以及预防和治疗肥胖、胰岛素抵抗和高血压等可能的合并症。本文概述了支持患有PCOS的青少年的结构化诊断检查和治疗方法。