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[毛细血管内和毛细血管外性亨诺肾炎患者的急性肾功能不全]

[Acute renal insufficiency in a patient with intra- and extracapillary Henoch's nephritis].

作者信息

Dimitrakov D, Vasilev I, Velichkova E

出版信息

Vutr Boles. 1985;24(5):99-103.

PMID:4090461
Abstract

Case is described with acute renal failure in Henoch's nephritis with intra- and extracapillary cellular proliferation. The disease was manifested with its classical picture: characteristic purpura, articular pains in the wrist and ankle joints, mucous-bloody diarrhea. The renal changes originated at the very beginning of the hemorrhagic vasculitis and clinically was manifested with acute renal failure and severe nephrotic syndrome. Under the effect of hemodialysis and complex drug treatment with cytostatics, glucocorticoids, anticoagulants, plasma- and bloodtransfusions, a very good clinical and paraclinical effect was attained. No recurrences of the main disease were recorded during the six-year clinical observation. A stability of the renal function was observed in the patient, with the exception of the persiting proteinuria with values under 10 g/l.

摘要

报道了1例伴有毛细血管内和外细胞增殖的过敏性紫癜肾炎合并急性肾衰竭的病例。该疾病表现为典型症状:特征性紫癜、手腕和踝关节疼痛、黏液血性腹泻。肾脏病变始于出血性血管炎的最初阶段,临床上表现为急性肾衰竭和严重肾病综合征。在血液透析以及使用细胞抑制剂、糖皮质激素、抗凝剂、血浆和输血进行综合药物治疗的作用下,取得了非常好的临床和辅助检查效果。在6年的临床观察期间未记录到主要疾病的复发情况。观察到患者肾功能稳定,仅有持续蛋白尿,值低于10g/L。

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