Chen Qiaoxia, Chen Juanjuan, Teng Yanjuan
Department of Nursing, Shanghai Sixth People's Hospital, Shanghai, 200233, People's Republic of China.
Int J Gen Med. 2025 Aug 28;18:4885-4892. doi: 10.2147/IJGM.S536545. eCollection 2025.
To investigate the risk factors of hypotension during maintenance hemodialysis in patients with end-stage chronic glomerulonephritis.
A total of 129 patients with end-stage chronic glomerulonephritis on maintenance hemodialysis admitted to our hospital from March 2022 to May 2024 were retrospectively analyzed, and the relevant clinical data of the patients were recorded. Univariate and multivariate logistic regression analysis were performed on various factors that may affect the occurrence of hypotension in patients, and the nomogram model was constructed. The receiver operating characteristic (ROC) curve was used to analyze the predictive risk of hypotension in patients with end-stage chronic glomerulonephritis on maintenance hemodialysis.
A total of 9186 times of dialysis were completed in 129 patients, and 597 times of intradialysis hypotension (IDH) occurred in 46 patients, with an incidence of 6.50%. The patients were divided into IDH group and No-IDH group according to whether they had intradialytic hypotension (IDH). Univariate and multivariate logistic regression analysis showed that ultrafiltration rate, weight growth rate, vascular access type and plasma albumin were independent risk factors for hypotension in patients. A nomogram model was constructed based on the above factors. The area under the curve (AUC) of the nomogram model for predicting intradialytic hypotension (IDH) was 0.862.
Ultrafiltration rate >10 mL/min, weight growth rate >3%, long-term catheter vascular access and low plasma albumin level are independent risk factors for hypotension in patients with end-stage chronic glomerulonephritis undergoing maintenance hemodialysis. The nomogram model based on these factors has a high application value in identifying patients at high risk of hypotension.
探讨终末期慢性肾小球肾炎患者维持性血液透析期间低血压的危险因素。
回顾性分析2022年3月至2024年5月我院收治的129例终末期慢性肾小球肾炎维持性血液透析患者，记录患者的相关临床资料。对可能影响患者低血压发生的各种因素进行单因素和多因素logistic回归分析，并构建列线图模型。采用受试者工作特征（ROC）曲线分析终末期慢性肾小球肾炎维持性血液透析患者低血压的预测风险。
129例患者共完成透析9186次，46例患者发生透析中低血压（IDH）597次，发生率为6.50%。根据是否发生透析中低血压（IDH）将患者分为IDH组和非IDH组。单因素和多因素logistic回归分析显示，超滤率、体重增长率、血管通路类型和血浆白蛋白是患者低血压的独立危险因素。基于上述因素构建列线图模型。列线图模型预测透析中低血压（IDH）的曲线下面积（AUC）为0.862。
超滤率>10 mL/min、体重增长率>3%、长期导管血管通路和低血浆白蛋白水平是终末期慢性肾小球肾炎维持性血液透析患者低血压的独立危险因素。基于这些因素的列线图模型在识别低血压高危患者方面具有较高的应用价值。
