Ueda Yukihiko
Okinawa International University, Ginowan, Ginowan-shi, Okinawa, Japan.
Intractable Rare Dis Res. 2025 Aug 31;14(3):203-209. doi: 10.5582/irdr.2025.01024.
This study examined the efficacy of a Mindfulness-Based Cognitive Behavioral Group Program (MCBGP) designed to improve the mental health of patients with intractable diseases. Adults ( = 35) with such diseases participated in the study. They were categorized into a high- or low-depression group based on the Profile of Mood States (POMS) depression subscale score of 60 as the cutoff score. MCBGP was conducted monthly over three sessions, each session lasting 120 minutes. Each session consisted of psychoeducation, self-disclosure, and mindfulness meditation. The program outcomes were evaluated using the Stanford University Chronic Disease Self-Management Questionnaire, the POMS, and the World Health Organization Quality of Life instruments. The results showed that in the high-depression group ( = 11), health distress ( = 0.013), activity limitations ( = 0.022), depression ( < 0.001), anxiety/tension ( = 0.002), anger/irritability ( = 0.004), fatigue ( = 0.023), and confusion ( = 0.033) were significantly reduced. The total quality of life scores were significantly improved ( = 0.028) after the program, whereas no significant improvements were observed in the low-depression group ( = 24). It was concluded that the MCBGP was effective in improving mental health outcomes and enhanced the quality of life in patients with intractable diseases and comorbid depression.
本研究考察了一项基于正念的认知行为团体项目（MCBGP）改善疑难病症患者心理健康状况的效果。患有此类疾病的成年人（ = 35）参与了该研究。根据情绪状态剖面图（POMS）抑郁分量表得分，以60分为临界值，将他们分为高抑郁组或低抑郁组。MCBGP每月进行一次，共三个疗程，每个疗程持续120分钟。每个疗程包括心理教育、自我表露和正念冥想。使用斯坦福大学慢性病自我管理问卷、POMS和世界卫生组织生活质量量表对项目结果进行评估。结果显示，在高抑郁组（ = 11）中，健康困扰（ = 0.013）、活动受限（ = 0.022）、抑郁（ < 0.001）、焦虑/紧张（ = 0.002）、愤怒/易怒（ = 0.004）、疲劳（ = 0.023）和困惑（ = 0.033）均显著降低。项目结束后，生活质量总分显著提高（ = 0.028），而低抑郁组（ = 24）未观察到显著改善。研究得出结论，MCBGP在改善心理健康结果以及提高疑难病症合并抑郁症患者的生活质量方面是有效的。
